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prothrombin fragment 1

N-terminal portion of prothrombin released on treatment with thrombin: 156 residues
Also Known As:
prothrombin profragment-1; Blood-coagulation factor II, fragment 1
Networked: 131 relevant articles (4 outcomes, 8 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1. De Palo, Micaela: 2 articles (04/2014 - 08/2012)
2. Guida, Pietro: 2 articles (04/2014 - 08/2012)
3. Paparella, Domenico: 2 articles (04/2014 - 08/2012)
4. Rotunno, Crescenzia: 2 articles (04/2014 - 08/2012)
5. Hatada, Tsuyoshi: 2 articles (11/2012 - 07/2008)
6. Nobori, Tsutomu: 2 articles (11/2012 - 07/2008)
7. Wada, Hideo: 2 articles (11/2012 - 07/2008)
8. Liu, Jihong: 2 articles (12/2011 - 01/2005)
9. Wang, Shaogang: 2 articles (12/2011 - 01/2005)
10. Wang, Tao: 2 articles (12/2011 - 01/2005)

Related Diseases

1. Venous Thrombosis (Deep-Vein Thrombosis)
2. Inflammation (Inflammations)
04/01/2014 - "Interleukin 6 (a marker of inflammation), prothrombin fragment 1-2 (a marker of thrombin generation), plasmin-antiplasmin complex (a marker of fibrinolysis), and platelet factor 4 (a marker of platelet activation) were measured at six different times. "
04/01/2004 - "We prospectively measured the plasma levels of activated factor XII, cleaved kininogen, prothrombin fragment 1 + 2 (as indexes of the contact phase and coagulation activation), and interleukin-6 and C-reactive protein (CRP) (as indexes of inflammation) in 39 patients hospitalized for AMI within 12 hours of symptom onset: 26 receiving thrombolytic therapy and 13 heparin alone. "
03/01/2006 - "The magnitude of the surgical trauma was assessed by measuring markers of coagulation (prothrombin fragment 1 + 2), endothelial activation (von Willebrand factor), inflammation [leukocytes, interleukin-6, -8 and -10, granulocyte macrophage colony-stimulating factor, and C-reactive protein (CRP)], and endocrine stress (cortisol) in blood collected before operation, 4 h postincision, and on postoperative day 2. Leukocyte counts and interleukin-6 and CRP levels increased in both groups, with the CRP increase being significantly greater in the OR group. "
08/01/2012 - "Myocardial damage was evaluated measuring cardiac troponin I. Interleukin (IL)-6 (a marker of inflammation), prothrombin fragment 1-2 (PF-1.2, a marker of thrombin generation), plasmin-antiplasmin complex (PAP, a marker of fibrinolysis), and platelet factor 4 (PF4, a marker of platelet activation) were measured. "
03/01/2003 - "In a prospective study, prothrombin fragment 1 and 2 (F1.2), thrombin-antithrombin complex (TAT), antithrombin, D-dimer, plasmin-alpha(2)-antiplasmin complex (PAP) and plasminogen activator inhibitor-1 (PAI-1) were measured in 20 patients with Crohn's disease (CD), 18 with ulcerative colitis (UC), and 19 with giant cell arteritis during active and inactive disease, as well as in 51 controls without inflammation. "
3. Hypertension (High Blood Pressure)
4. Wounds and Injuries (Trauma)
5. Hypoglycemia (Reactive Hypoglycemia)

Related Drugs and Biologics

1. Thrombin
2. fibrin fragment D (D-dimer)
3. von Willebrand Factor
4. Antithrombins
5. Antithrombin III
6. Fibrinogen (Factor I)
7. C-Reactive Protein
8. Interleukin-6 (Interleukin 6)
9. Plasminogen Activators (Plasminogen Activator)
10. Heparin (Liquaemin)

Related Therapies and Procedures

1. Therapeutics
2. Drug Therapy (Chemotherapy)
3. Aftercare (After-Treatment)
4. Hip Replacement Arthroplasty (Total Hip Replacement)
5. Mammaplasty (Breast Reconstruction)