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12-deoxyphorbolphenylacetate-20-acetate
Also Known As:
12-DOPPAA; 12-deoxyphorbol 13-phenylacetate 20-acetate
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Hydrocarbons: 1713
Terpenes: 1461
Diterpenes: 1470
Phorbols: 26
Phorbol Esters: 2726
12-deoxyphorbolphenylacetate-20-acetate: 1
Related Diseases
1.
Erythema
01/01/1981 - "
Indomethacin was only partly successful as an antagonist since 10% inhibition of 12-DOPPA and no inhibition of 12-DOPPAA induced erythema was produced four hours after application.
"
01/01/1981 - "
The pro-inflammatory tigliane esters 12-deoxyphorbolphenylacetate (12-DOPPA) and 12-deoxyphorbolphenylacetate-20-acetate (12-DOPPAA) at a dose of 0.1 microgram induced erythema in the mouse ear.
"
01/01/1981 - "
Mepyramine and cyproheptadine also failed to inhibit the erythema, whereas hydrocortisone produced a 55% inhibition of the 12-DOPPA and a 20% inhibition of the 12-DOPPAA reaction.
"
01/01/1981 - "
The membrane stabilising agents trifluoperazine, promethazine, imipramine and desmethylimipramine were the most successful compounds used in inhibiting both 12-DOPPA and 12-DOPPAA induced erythema.
"
01/01/1981 - "
The free radical scavengers, phenol, thioanisole and sodium benzoate all produced less than 30% inhibition of 12-DOPPA induced erythema and less than 15% inhibition of 12-DOPPAA, whereas aminopyrine produced 70% and 25% inhibition of 12-DOPPA and 12-DOPPAA respectively.
"
Related Drugs and Biologics
1.
Sodium Benzoate
2.
Phenol (Carbolic Acid)
3.
Free Radical Scavengers
4.
Trifluoperazine (Stelazine)
5.
Pyrilamine (Mepyramine)
6.
Promethazine (Promet)
7.
Phorbols
8.
Indomethacin (Indometacin)
9.
Imipramine (Janimine)
10.
Hydrocortisone (Cortisol)