urotensin II

11/01/2009 - "The sources of secretion and clearance of plasma urotensin II (UII) in the human circulation remain uncertain and may be relevant to understanding the role of UII in human physiology and cardiovascular disease. "
05/01/2008 - "Although future studies are required to clarify whether these mechanisms are also important in the clinical setting, this report supports an emerging new role for urotensin II in the pathogenesis and progression of cardiovascular disease."
05/01/2015 - "Blockade of the actions of urotensin-II (U-II) mediated by the urotensin (UT) receptor should improve cardiac function and prevent cardiac remodelling in cardiovascular disease. "
07/01/2013 - "Urotensin II (UII) is a potent vasoconstrictive peptide that also promotes the inflammatory process in patients with cardiovascular disease. "
09/25/2009 - "Expression of the vasoactive peptide Urotensin II (UII) is elevated in a number of cardiovascular diseases. "

01/01/2015 - "Plasma urotensin II (UII) has been observed to be raised in patients with acute myocardial infarction; suggesting a possible cardiac protective role for this peptide. "
05/02/2007 - "Urotensin II is raised in acute myocardial infarction and low levels predict risk of adverse clinical outcome in humans."
08/01/2010 - "Urotensin II (UII) is a potential mediator in the pathogenesis of cardiovascular disease, and inhibition of its actions at the urotensin receptor (UT) has been shown to improve cardiac function and structural changes of the myocardium in a model of myocardial infarction. "
03/01/2008 - "In patients with acute cardiac ischemia, circulating urotensin II is lower than normal and low plasma urotensin II signals a higher risk of adverse clinical events following myocardial infarction. "
06/16/2006 - "Exercise urotensin II dynamics in myocardial infarction survivors with and without hypertension."

03/01/2008 - "The plasma urotensin-II level, maximal IMT, plaque score, systolic and diastolic blood pressure, and homeostasis model assessment for insulin resistance (HOMA-IR) were significantly greater in hypertensive patients than in normotensive controls. "
11/01/2013 - "The relationship of urotensin II with insulin resistance and hs-CRP in patients having PCOS."
01/01/2011 - "Association analysis of urotensin II gene (UTS2) and flanking regions with biochemical parameters related to insulin resistance."
09/01/2015 - "Previous studies showed that circulating urotensin II (UII) levels were increased in diabetes, and UII could inhibit the glucose transport in skeletal muscle in diabetic mice and aggravated insulin resistance. "
07/01/2006 - "Haplotypes in the urotensin II gene and urotensin II receptor gene are associated with insulin resistance and impaired glucose tolerance."

01/01/2013 - "The purpose of this study is to present whether the serum urotensin II levels are different in patients with dipper and non-dipper hypertension and to put forward the effects causing this difference, if there are any. "
11/01/2003 - "Therefore, in this study, we aimed to quantify and compare plasma and CSF urotensin II concentrations in patients with essential hypertension and matched controls. "
01/01/2013 - "Urotensin II (UII) concentrations are raised both in humans with hypertension and in spontaneously hypertensive rats (SHR). "
01/01/2013 - "Our results indicated that urotensin II might be an independent risk factor for essential hypertension."
01/01/2013 - "In multivariate regression analysis, subjects in the highest quartile of urotensin II were more likely to have hypertension than those in the lowest quartile (OR, 2.58; 95% CI, 1.21-5.49). "

10/03/2014 - "Recent studies showed that Urotensin II (U II) is involved in the pathogenesis of atherosclerosis. "
05/01/2013 - "Urotensin II receptor antagonism confers vasoprotective effects in diabetes associated atherosclerosis: studies in humans and in a mouse model of diabetes."
01/01/2015 - "Circulating urotensin II (UII) is involved in the development of atherosclerosis. "
11/01/2013 - "Urotensin-II (UII) is a vasoactive peptide that promotes vascular smooth muscle cells (VSMCs) proliferation and is involved in the pathogenesis of atherosclerosis, restenosis, and vascular remodelling. "
05/01/2013 - "The small, highly conserved vasoactive peptide urotensin II (UII) is upregulated in atherosclerosis. "