zearalenol

RN given refers to (3S-(3R*,7S*,11E))-isomer

Also Known As:

(-)-beta-zearalenol; (3R,7R,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one; 1H-2-benzoxacyclotetradecin-1-one, 3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-, (3S,7R,11E)-; 3,4,5,6,7,8,9,10-octahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one; alpha-zearalenol; alpha-zearalenol, (cis)-isomer; beta-trans-zearalenol; beta-zearalenol

Networked: 21 relevant articles (1 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Phenols: 677
        Resorcinols: 4
        Zearalenone: 227
        Zeranol: 71
        zearalenol: 21
- Lactones: 1549
  - Zearalenone: 227
    - Zeranol: 71
      - zearalenol: 21

Experts

1.	Juan, Cristina: 2 articles (10/2021 - 10/2021)
2.	Juan-García, Ana: 2 articles (10/2021 - 10/2021)
3.	Brzuzan, Paweł: 1 article (01/2022)
4.	Gajęcka, Magdalena: 1 article (01/2022)
5.	Gajęcki, Maciej T: 1 article (01/2022)
6.	Leski, Dawid: 1 article (01/2022)
7.	Lisieska-Żołnierczyk, Sylwia: 1 article (01/2022)
8.	Mróz, Magdalena: 1 article (01/2022)
9.	Zielonka, Łukasz: 1 article (01/2022)
10.	Alvarez-Ortega, Neda: 1 article (10/2021)

Related Diseases

1.	Neuroblastoma 10/22/2021 - "Protective Effects of the Hydroethanolic Extract of Fridericia chica on Undifferentiated Human Neuroblastoma Cells Exposed to α-Zearalenol (α-ZEL) and β-Zearalenol (β-ZEL)." 10/01/2021 - "Coffee silverskin and spent coffee have been evaluated in a neuroblastoma cell line (SH-SY5Y cells) against beauvericin (BEA) and α-zearalenol (α-ZEL)-induced cytotoxicity with different strategies of treatment. "
2.	Hepatocellular Carcinoma (Hepatoma) 12/01/2017 - "This study explores oxidative cellular damage and intracellular defense mechanisms (enzymatic and non-enzymatic) in the hepatoma cell line HepG2 after exposure to ZEA and its metabolites (α-zearalenol, α-ZOL; β-zearalenol, β-ZOL). " 06/15/2020 - "We investigated the effects of zearalenone and its metabolite alpha zearalenol on epigenetic modifications and its relationship with metabolic pathways in human hepatocellular carcinoma cells following 24 h of exposure. "
3.	Mycotoxicosis (Fungus Poisoning) 11/11/2022 - "This study was undertaken to analyze whether prolonged exposure to low-dose zearalenone (ZEN) mycotoxicosis affects the concentrations of ZEN, α-zearalenol (α-ZEL), and β-zearalenol (β-ZEL) in selected reproductive system tissues (ovaries, uterine horn-ovarian and uterine sections, and the middle part of the cervix), the hypothalamus, and pituitary gland, or the concentrations of selected steroid hormones in pre-pubertal gilts. "
4.	Carcinoma (Carcinomatosis) 09/01/2002 - "In this study, the quantity of zearalenone and its congeners (alpha-zearalenol and beta-zearalenol) present in the plasma of patients with breast (n = 28) and cervical carcinoma (n=54) were compared with levels in patients presenting with other diagnoses (n = 26) and healthy volunteers (n = 24). "
5.	Breast Neoplasms (Breast Cancer) 01/01/2018 - "Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach." 03/01/2009 - "In cell culture, Zen and its metabolite, alpha-Zearalenol (alpha-Zel), stimulate breast cancer cells growth. " 03/01/2016 - "zearalenone and both zearalenol isomers) when exposed to breast cancer cells culture. " 06/01/2015 - "The aim of this case-control study was to estimate exposure to ZON and its five metabolites (α-zearalenol [α-ZOL], β-zearalenol [β-ZOL], α-zearalanol [zeranol, α-ZAL], β-zearalanol [teranol, β-ZAL] and zearalanone [ZAN]) by measuring urinary concentrations of these compounds, and to evaluate the risk of breast cancer related to this exposure. " 12/15/2005 - "In order to characterize the estrogenic activity of zearalenone and its derivatives (alpha-zearalenol (alpha-ZEA), beta-zearalenol (beta-ZEA), alpha-zearalanol (alpha-ZAL) and beta-zearalanol (beta-ZAL)), the proliferation of ER-positive (MCF-7) and ER-negative (MDA-MB-231) human breast cancer cell lines was measured. "

Related Drugs and Biologics

1.	Zearalenone
2.	zearalenol
3.	Steroids
4.	Hormones (Hormone)
5.	Mycotoxins
6.	Zeranol
7.	Vitellogenins (Vitellogenin)
8.	Enzymes
9.	taleranol
10.	Messenger RNA (mRNA)