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hydrazine (hydrazine dihydrochloride)

used as fuel in emergency power systems; see also record for hydrazine sulfate RN: 10034-93-2; RN given refers to parent cpd

Also Known As:

hydrazine dihydrochloride; hydrazine hydrate; hydrazine sulfate; hydrazine monohydrate; hydrazine mononitrate; hydrazine nitrate; hydrazine phosphate (1:1); hydrazine phosphate (2:1); hydrazine sulfate (1:1) monosodium salt; hydrazine sulfate (2:1); hydrazine tartrate; segidrin

Networked: 398 relevant articles (11 outcomes, 44 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrazines: 39
  - hydrazine: 398

Experts

1.	Penketh, Philip G: 6 articles (11/2011 - 01/2005)
2.	Shyam, Krishnamurthy: 6 articles (11/2011 - 01/2005)
3.	Sartorelli, Alan C: 6 articles (11/2011 - 01/2005)
4.	Baumann, Raymond P: 5 articles (11/2011 - 01/2005)
5.	Ishiguro, Kimiko: 4 articles (10/2011 - 11/2005)
6.	Wojtasek, Hubert: 3 articles (01/2014 - 06/2008)
7.	Sudhandiran, Ganapasam: 2 articles (05/2015 - 03/2014)
8.	Prasad, V Ganga: 2 articles (05/2015 - 01/2014)
9.	Rao, C Mallikarjuna: 2 articles (05/2015 - 01/2014)
10.	Jayashree, B S: 2 articles (05/2015 - 01/2014)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1975 - "In a series of 84 various evaluable disseminated cancer patients treated with hydrazine sulfate as a result of a pharmaceutical-sponsored investigational new drug (IND) study, it was found that 59/84 or 70% of the cases improved subjectively and 14/84 or 17% improved objectively. " 12/05/2000 - "To report a case of fulminant hepatorenal failure associated with the use of hydrazine sulfate, an unregulated alternative remedy for cancer marketed on the Internet. " 01/01/1976 - "On the relationship between the activity of acetylation, growth of experimental tumors and efficacy of their suppression by hydrazine sulphate." 03/01/2006 - "Animal studies suggest that hydrazine is a lung carcinogen, but human studies have been rare, rather small, and limited to cancer mortality. " 07/01/1986 - "The most active compound to emerge from this study, 2-[(4-chlorophenyl)sulfonyl]-1-methyl-1-(4-tolylsulfonyl)hydrazine , increased the survival time of tumor-bearing mice by 88%. "
2.	Tuberculosis (Tuberculoses) 01/01/1955 - "Further studies on the use of streptomycylidene isonicotinyl hydrazine sulfate in the treatment of tuberculosis." 01/01/1952 - "Clinical studies: treatment of tuberculosis with isonicotinic acid hydrazine and its derivatives." 01/01/1952 - "Studies on the activity of hydrazine derivatives of isonicotinic acid in the experimental tuberculosis of mice." 01/01/2014 - "In order to develop a lead antimycobacterium tuberculosis compound, a series of 52, novel pyrrole hydrazine derivatives have been synthesized and screened which target the essential enoyl-ACP reductase. " 01/01/1992 - "Factors in hydrazine formation from isoniazid by paediatric and adult tuberculosis patients."
3.	Pulmonary Tuberculosis 10/01/1956 - "Further experiences with the clinical use of streptomycylidene isonicotinyl hydrazine sulfate in the therapy of pulmonary tuberculosis." 12/01/1954 - "The use of intermittent (twice weekly) streptomyclidene isonicotyl hydrazine sulphate in the treatment of pulmonary tuberculosis (without oral INH)." 10/01/1954 - "The intermittent use of streptomycylidene isonicotinyl hydrazine sulfate in the therapy of pulmonary tuberculosis." 01/01/1954 - "[Treatment of pulmonary tuberculosis by isonicotinyl isopropyl hydrazine]." 01/01/1953 - "Isonicotinyl hydrazine in the treatment of pulmonary tuberculosis in children; a preliminary report."
4.	Body Weight (Weight, Body) 03/01/2011 - "Group 2 received 1,2-dimethyl hydrazine (20 mg/kg body weight) subcutaneously once a week for four weeks. " 01/01/1987 - "in Massachusetts, USA, were fasted overnight and given 0, 5, 10, 20, or 40 mg hydrazine per kg body weight by intraperitoneal injection and decapitated 24 hr later. " 02/01/1987 - "These data, which demonstrate an association between 1 month of hydrazine sulfate administration and body weight maintenance in patients with cancer, suggest future clinical trials of hydrazine sulfate are indicated to definitively assess its long-term impact on important clinical outcome parameters in defined cancer populations." 01/01/1976 - "Inhibition of carcinosarcoma Walker-256 by 88% and sarcoma-180 by 36% on treatment with 60 mg/kg body weight of hydrazine sulphate was followed by decreases in the rate of acetylation of 39.4 and 29.4%, respectively. " 03/01/2011 - "Groups 4 to 6 were given a daily oral dose of 50, 100, 200 mg/kg body weight of kaempferol with 1,2-dimethyl hydrazine. "
5.	Anorexia 09/01/2003 - "Currently, the clinical efficacy of cyproheptadine, hydrazine and pentoxyfilline in the treatment of anorexia is uncertain. " 03/01/1995 - "Despite positive pilot trial reports, large randomized studies have been unable to demonstrate a clinically defensible role for either pentoxifylline, cyproheptadine, or hydrazine sulfate for patients with anorexia. " 04/01/1992 - "Efforts are also ongoing to evaluate both anabolic steroids and hydrazine sulfate as drugs for the treatment of patients with cancer anorexia/cachexia. " 11/01/1993 - "Cyproheptadine, hydrazine sulfate, and cannabinoids also are being studied in the management of cancer-induced anorexia, but their role has not yet been clearly established. " 01/01/1992 - "Cyproheptadine, hydrazine sulfate, and cannabinoids also are being studied in the management of cancer-induced anorexia, but their role has not yet been clearly established. "

Related Drugs and Biologics

1.	Isonicotinic Acids (Isonicotinic Acid)
2.	Immunoglobulin G (IgG)
3.	Isoniazid (Ftivazide)
4.	Cyproheptadine (Periactin)
5.	laromustine (VNP40101M)
6.	Dihydrostreptomycin Sulfate (Dihydrostreptomycin)
7.	irinotecan (Camptosar)
8.	kaempferol
9.	Hydralazine (Apresoline)
10.	Adenosine Diphosphate (ADP)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Chemoprevention
3.	Transplants (Transplant)
4.	Oral Administration
5.	Nutritional Support (Artificial Feeding)