feline oncornavirus-associated cell membrane antigen

06/17/1977 - "Thus, FOCMA expression in mind lung cells is specifically associated with transformation by feline sarcoma virus."
10/01/1976 - "Immunized cats produced high antibody titers to the feline oncornavirus-associated cell membrane antigen and were protected from oncogenic feline sarcoma virus challenge. "
06/17/1977 - "Transformation of the same cells by murine sarcoma virus, or infection with feline leukemia virus, which is nontransforming for epithelial or fibroblastic cells, did not induce FOCMA. "
02/01/1976 - "A clear correlation has been shown between the resistance of cats to development of lethal tumors following inoculation of feline sarcoma virus and the presence of high humoral antibody titers to FOCMA. "
12/01/1977 - "In the present study, mink and rat cells nonproductively transformed by feline sarcoma virus (FeSV) were shown to express FOCMA as well as 5'-terminal feline leukemia virus (FeLV) gag gene proteins, p15 and p12. "

01/30/1983 - "FeLV-negative tumors not expressing FeLV C gp70 were also FOCMA negative. "
08/01/1982 - "In a smaller number of patients, there was no evidence of antibody to FOCMA or of FOCMA on tumor cells in the bone marrow."
03/01/1979 - "Groups of cats were immunized with either killed feline oncornavirus-associated cell membrane antigen bearing tumor cells or tumor cells plus FeLV p15. "
04/01/1976 - "Animals with neoplasms were low or negative for FOCMA antibody and did not have high titers of free p30 antibody. "
12/01/1975 - "Conversely, animals in the regressor group or group with no tumors were more likely to show an early rise in detectable anti-FOCMA activity than animals in either of the progressor groups."

03/01/2010 - "In 7 of the 20 remaining cats FOCMA assay positivity was the only sign of infection, while all other tests were negative. "
04/01/1981 - "The presence in nonviremic cats of FeLV gsa in sera and FOCMA in BM and sera suggests that these cats may have a persistent, low-level FeLV infection."
01/01/1981 - "As early as 10 days after infection, when more than half of the infected cells were gsa positive, FOCMA was detected on 5-10 percent of the cells. "
01/01/1981 - "Infection of feline embryo adherent cells with feline leukemia virus: feline oncornavirus-associated cell membrane antigen expression and morphologic transformation."
11/01/1976 - "Antibody to FOCMA developed following FeLV infection and was expressed in heterologous species. "

02/01/1976 - "Conversely, some cats resist development of leukemia or lymphoma following natural exposure to feline leukemia virus in leukemia cluster households, and these cats have high FOCMA antibody titers. "
02/01/1976 - "Cats with induced or spontaneous leukemia or lymphoma also have either no detectable FOCMA antibody or very low levels. "
08/01/1975 - "No significant differences were found in geometric mean FOCMA antibody titers for the various forms of leukemia-lymphoma or for feline leukemia virus (FeLV)-positive as compared to FeLV-negative cats. "
01/30/1983 - "Feline oncornavirus-associated cell membrane antigen: a viral and not a cellularly coded transformation-specific antigen of cat lymphomas."
12/01/1980 - "Several individually derived feline lymphoma cell lines were used as targets for CDA-FOCMA, and the results suggested that lytic activity is directed to multiple antigen determinants expressed differently by individual feline lymphomas."

04/01/1976 - "In contrast to the general lack of free antibody to FeLV p30 in a random sample of healthy cats, high levels of antibody to FeLV p30 and FOCMA were found in normal animals from high-leukemia-cluster households. "
11/21/1975 - "When compared to their housemates that subsequently developed leukemia, cats that remained healthy had five-to tenfold higher (geometric mean) humoral antibody titers to the feline oncornavirus-associated cell membrane antigen. "
02/01/1976 - "Conversely, some cats resist development of leukemia or lymphoma following natural exposure to feline leukemia virus in leukemia cluster households, and these cats have high FOCMA antibody titers. "
02/01/1976 - "Cats with induced or spontaneous leukemia or lymphoma also have either no detectable FOCMA antibody or very low levels. "
08/01/1975 - "No significant differences were found in geometric mean FOCMA antibody titers for the various forms of leukemia-lymphoma or for feline leukemia virus (FeLV)-positive as compared to FeLV-negative cats. "