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asparaginyl-tRNA synthetase

Subscribe to New Research on asparaginyl-tRNA synthetase

GenbBank AJ222644 (Arabidopsis); RefSeq NM_004539 (human)

Also Known As:

ATNS1 protein, Arabidopsis; Asn-tRNA synthetase; AsnRS enzyme; Asparaginyl-tRNA synthetase protein, Arabidopsis; Cytosolic asparaginyl-tRNA synthetase protein, S cerevisiae; DED81 protein, S cerevisiae; L-asparaginyl tRNA synthetase; Mitochondrial asparaginyl-tRNA synthetase protein, S cerevisiae; NARS protein, human; NS1 protein, Arabidopsis; YCR024C protein, S cerevisiae; YHR019C protein, S cerevisiae; asparagine - tRNA ligase; asparagine-tRNA synthetase; asparaginyl tRNA synthetase; asparaginyl-tRNA synthetase protein, human; cytosolic asparaginyl-tRNA synthetase protein, human

Networked: 10 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Kron, Michael: 3 articles (04/2011 - 09/2002)
2.	Kron, Michael A: 2 articles (02/2013 - 01/2005)
3.	Vodanovic-Jankovic, Sanja: 2 articles (02/2013 - 04/2011)
4.	Oppenheim, Joost J: 2 articles (06/2005 - 09/2002)
5.	Dong, Hui Fang: 2 articles (06/2005 - 09/2002)
6.	Howard, O M Zack: 2 articles (06/2005 - 09/2002)
7.	Petridis, Michael: 2 articles (01/2005 - 06/2003)
8.	Härtlein, Michael: 2 articles (06/2003 - 09/2002)
9.	Abdenur, Jose: 1 article (03/2015)
10.	Davila, Antonio: 1 article (03/2015)

Related Diseases

1.	Myositis (Idiopathic Inflammatory Myopathies) 01/01/2005 - "A subset of patients with idiopathic inflammatory myopathies demonstrate autoantibody against specific cytoplasmic AARS and the human asparaginyl-tRNA synthetase (AsnRS) has been shown to be a potent chemokine that interacts with CCR3 chemokine receptors. " 09/16/2002 - "Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells." 06/01/2005 - "Our initial observation that myositis-associated autoantigens, histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, were chemotactic for CC chemokine receptor 5 (CCR5)- and CCR3-expressing leukocytes, while other nonautoantigenic aminoacyl-tRNA synthesases were not, suggested that only self-antigens capable of interacting with receptors on antigen-presenting cells were immunogenic. "
2.	Filarial Elephantiasis (Lymphatic Filariasis) 04/15/2011 - "Lymphatic filariasis is caused by the parasitic nematodes Brugia malayi and Wuchereria bancrofti, and asparaginyl-tRNA synthetase (AsnRS) is considered an excellent antifilarial target. " 06/01/2003 - "In Brugia malayi, the gene for asparaginyl-tRNA synthetase (AsnRS), a class II AARS, previously has been identified as a multicopy gene encoding an immunodominant antigen in the serum of humans with lymphatic filariasis. "
3.	Hearing Loss (Hearing Impairment) 03/01/2015 - "Here we demonstrate association of variants in the mitochondrial asparaginyl-tRNA synthetase NARS2 with human hearing loss and Leigh syndrome. "
4.	Leigh Disease (Leigh's Disease) 03/01/2015 - "Here we demonstrate association of variants in the mitochondrial asparaginyl-tRNA synthetase NARS2 with human hearing loss and Leigh syndrome. " 03/01/2015 - "Mutations of human NARS2, encoding the mitochondrial asparaginyl-tRNA synthetase, cause nonsyndromic deafness and Leigh syndrome."
5.	Inflammation 02/01/2013 - "Nematode asparaginyl-tRNA synthetase resolves intestinal inflammation in mice with T-cell transfer colitis."

Related Drugs and Biologics

1.	Chemokine Receptors
2.	Histidine-tRNA Ligase
3.	Autoantigens
4.	CCR5 Receptors (CCR5 Receptor)
5.	Transfer RNA (tRNA)
6.	Antigens
7.	Anticodon
8.	prolyl T RNA synthetase

Related Therapies and Procedures

1.	Chinese Traditional Medicine (Traditional Chinese Medicine)