phytohemagglutinin-P

01/01/1984 - "Mitogen studies with 9098 tumor-bearing animals, which were treated with NSP, showed that the PHA-P mitogenic reactivity of spleen cells from NSP treated tumor bearing rats (TBR) was higher than that from NSP untreated TBR. "
03/01/1975 - "In all groups regional lymph node lymphocytes showed the earliest peak response to PHA-P and autologous tumor, while the splenic lymphocyte and distant lymphocyte responses were delayed, especially in Group III. These studies demonstrate the role of the regional lymph node in the initial processing of tumor antigenic information. "
09/01/1989 - "In these four patients, this lymphocyte blastogenetic response to tumor cells were at a much lower level compared with phytohemagglutinin P or allogeneic lymphocyte stimulation. "
09/01/1986 - "However, parenchymal T11 and T4 cell infiltration was less in advanced primary tumors (T3, T4) than in early tumors (T1, T2) (P = 0.01, P = 0.067, respectively), as was peripheral lymphocyte reactivity to PHA (P = 0.013). "
01/01/1984 - "The PHA-P response of popliteal lymph node cells proximal to the tumor lesion was fairly low compared with the splenic PHA-P response and there was no difference between the lymphocytes from mice whose tumors had regressed or progressed. "

01/01/1992 - "The mice were divided in two groups: nonstimulated and stimulated intraperitoneally with PHA-P at dose 10 mg/kg body weight. "
04/01/1988 - "Cortisol produced a significantly greater CBH response in Trials 1 and 2 as indicated by higher wattle indices at 48 h and at 6 h in Trial 3. Regression analysis indicated significantly greater intercepts for the cortisol responses in Trials 1 and 3 and a significantly greater linear component for the cortisol response in Trial 2. Body weights and relative bursa and spleen weights were reduced significantly by cortisol, whereas relative adrenal weights were increased significantly in Trials 2 and 3. These data indicated that cortisol enhanced CBH to the mitogen PHA-P in broiler cockerels. "
02/01/1997 - "Body weights, total erythrocyte counts, blood urea nitrogen (BUN) levels, and in vitro mitogenic response to PHA-P and Con A were higher in the F line birds. "
04/01/1988 - "At 6 wk of age, chicks were injected intramuscularly with 2 mg of cortisol in a corn oil vehicle/500 g body weight at 48, 36, 24, and 12 h prior to challenge with PHA-P. "
12/01/1983 - "Bacto-phytohemagglutinin-P (PHA-P) was administered in form of a single intralumbar injection of 2 mg/100 g body weight dose to 24- to 28-mth-old female CGY rats. "

04/01/1982 - "Intestinal lymphocytes from patients with Crohn's disease demonstrated a significantly greater response to phytohemagglutinin-P than lymphocytes isolated from non-Crohn's patients. "
10/15/1982 - "Phytohaemagglutinin-P (PHA-P) transformation characteristics of intestinal lymphoid cells and those of peripheral blood were studied in 20 patients with Crohn's disease and 10 control subjects. "
12/15/1978 - "The results indicate an immune defect of lymphocyte function and the effect of humoral factor(s) on T cell mediated immune reactions: (1) Lymphocyte stimulation by PHA-P was reduced significantly in Crohn's disease. "
12/15/1978 - "In 20 patients suffering for several years from serious chronic relapsing Crohn's disease the following immunological tests were carried out: (1) in-vitro stimulation of blood lymphocytes by PHA-P, (2) identification of T and B cells by formation of spontaneous rosettes and complement receptor rosettes, (3) effect of Crohn's serum on mixed lymphocyte reaction (MLR) of normal allogeneic lymphocytes, (4) in-vitro phagocytosis and intracellular killing of E. "
02/01/1976 - "Lymphocytes from normal and abnormal human gut mucosa were stimulated by phytohemagglutinin-P, except in some patients with Crohn's disease with high rates of "spontaneous" DNA synthesis. "

04/01/1984 - "The group of 18 transplant recipients with skin cancer, when compared with transplant recipients with no cancer at a comparable period after transplant, showed similar depression of SCMC and ADCC activity, but significantly greater depression of responsiveness to PHA (P less than 0.01), allogeneic lymphocytes (P less than 0.05), and the 2 antigen cocktails (P less than 0.05)."

11/01/2008 - "In trial 3, an increase in the relative weight of bursa of Fabricius and phytohemagglutinin-P-inducing cutaneous basophil hypersensitivity was observed (P < 0.05). "
09/29/2008 - "The delayed type hypersensitivity response to 2,4-dinitro-1-chlorobenzene or to PHA-P was also significantly decreased. "
11/01/2003 - "Old dogs displayed lower delayed-type hypersensitivity test (DTH) responses versus younger controls to both phytohemagglutinin-P (PHA; 11.1 +/- 0.95 versus 7.57 +/- 1.15 mm; young-control versus old-control, respectively; P < .05) and sheep red blood cell (RBC; 9.12 +/- 0.62 versus 8.08 +/- 0.75 mm; young-control versus old-control, respectively; P < .10). "
05/01/2003 - "A cutaneous basophil hypersensitivity reaction to phytohemagglutinin (PHA-P) was measured to evaluate the cellular immune response. "
12/01/2002 - "The cutaneous basophil hypersensitivity (CBH) reaction to phytohemagglutinin (PHA-P) and primary antibody responses to Chukar red blood cells (CRBC) were determined at five intervals; 0, 1, 7, 14, and 21 d posthatch. "