flavanone

11/01/2014 - "The association for flavanone intake was stronger for serous invasive and poorly differentiated tumors (comparable HR: 0.68; 95% CI: 0.50, 0.92; P-heterogeneity = 0.10, P-trend = 0.07) compared with nonserous and less-aggressive tumors. "
01/01/2013 - "These findings could be used for designing cancer therapeutic or preventive flavanone-derived agents."
01/01/2013 - "In addition, new structural modification at C-4 of flavanone results in improving both the anti-cancer effect and anti-oxidative effect. "
06/01/2007 - "The structure was elucidated as (2S)-5,2',6'-trihydroxy-6-lavandulyl-4''-(gamma,gamma-dimethylallyl)-2'',2''-dimethylpyrano-[5'',6'' : 7,8]-flavanone by spectroscopic methods including UV, IR, HR-EI-MS, ESI-MS, 1D NMR and 2D NMR techniques, and subsequently, the anticancer activities of the compound to inhibit human cancer cells' growth including A549, BEL-7402, SGC-7901, MCF-7, HT-29, K562, and A498 cell lines by MTT method was evaluated in vitro."
11/01/2006 - "Flavanone metabolism in healthy and tumor-bearing rats."

10/01/2012 - "We also examined silibinin (100μg), a non-toxic natural flavanone found to be effective in treating SM analog-induced skin injuries in our earlier studies. "
04/01/2003 - "Analysis of crude wound wood extracts by HPLC coupled to negative ion electrospray mass spectrometry revealed the presence of a complex mixture of many unidentified formylated phlorglucinol compounds (FPCs), in addition to a diverse range of other polyphenolic compounds (hydrolyzable tannins, proanthocyanidins, flavanone glycoside, stilbene glycosides). "

04/01/2015 - "A class of flavanone was found to improve melanogenesis in B16F10 mouse melanoma cell line, but little is known about its target. "
01/01/2009 - "In a search for novel anticancer compounds from medicinal plants, the isolated flavanone was tested for cytotoxic activity against 57 human tumour lines, representing leukaemia, non-small cell lung, colon, central nervous system, melanoma, ovarian, renal, prostate and breast cancers. "
11/15/2011 - "Citrus flavanone naringenin enhances melanogenesis through the activation of Wnt/β-catenin signalling in mouse melanoma cells."

06/01/2010 - "Silibinin, a naturally occurring flavanone isolated from milk thistle extract, has been shown to possess strong anticancer efficacy against both androgen-dependent and androgen-independent prostate cancer, wherein it inhibits not only cell growth, but also cell invasion and metastasis. "
02/16/2006 - "Silymarin and silibinin cause G1 and G2-M cell cycle arrest via distinct circuitries in human prostate cancer PC3 cells: a comparison of flavanone silibinin with flavanolignan mixture silymarin."

06/01/2010 - "Silibinin, a naturally occurring flavanone isolated from milk thistle extract, has been shown to possess strong anticancer efficacy against both androgen-dependent and androgen-independent prostate cancer, wherein it inhibits not only cell growth, but also cell invasion and metastasis. "
05/01/2007 - "In conclusion, flavanone and 2'-OH flavanone perturb the invasion and metastasis of lung cancer cells, thereby constituting an adjuvant treatment for metastasis control."
05/01/2007 - "Finally, oral administration of flavanone and 2'-OH flavanone were evidenced by its inhibition on the metastasis of A549 cells and Lewis lung carcinoma (LLC) cells in vivo. "
05/01/2007 - "Flavanone and 2'-OH flavanone inhibit metastasis of lung cancer cells via down-regulation of proteinases activities and MAPK pathway."