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bathocuproine sulfonate

reagent for copper; RN given refers to parent cpd

Also Known As:

bathocuproine disulfonate; bathocuproine disulfonic acid, disodium salt; bathocuproine sulfonate, disodium salt

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 3-Ring Heterocyclic Compounds
    - Phenanthrolines: 183
      - bathocuproine sulfonate: 5

Experts

1.	Fukuda, Takeshi: 1 article (04/2013)
2.	Honda, Ken-Ichi: 1 article (04/2013)
3.	Ishiko, Osamu: 1 article (04/2013)
4.	Sumi, Toshiyuki: 1 article (04/2013)
5.	Teramae, Masatomo: 1 article (04/2013)
6.	Yamauchi, Makoto: 1 article (04/2013)
7.	Yasui, Tomoyo: 1 article (04/2013)
8.	Yoshida, Hiroyuki: 1 article (04/2013)

Related Diseases

1.	Lymphoma (Lymphomas) 05/15/1985 - "Three new cell lines have been established from patients with malignant lymphoma utilizing a human diploid feeder layer, pooled human serum, and the chemical supplements L-cysteine, iron-saturated transferrin, and bathocuproine disulfonate, a copper chelator. " 08/15/1985 - "With the use of bathocuproine sulfonate, a copper-specific chelator as an indicator, we have demonstrated that copper ions, present as a natural medium constituent are toxic to the growth of a lymphoma in primary culture and are principally responsible for the growth requirement of mercaptoethanol and other thiols. "
2.	Cysts 09/01/1990 - "Bathocuproine disulfonate also increased the total uptake and metabolism of cysteine plus cystine [cyst(e)ine] by hepatocytes, which is consistent with the more efficient transport of cysteine than of cystine by freshly isolated rat hepatocytes. " 09/01/1990 - "Effect of bathocuproine disulfonate, a copper chelator, on cyst(e)ine metabolism by freshly isolated rat hepatocytes." 12/01/1989 - "Cystine was the major extracellular form of cyst(e)ine present during the incubation, and addition of bathocuproine disulfonate, a copper chelator that maintained 60% of the total cyst(e)ine in the sulfhydryl form, had no effect on total sulfur release from cyst(e)ine. "
3.	Ovarian Neoplasms (Ovarian Cancer) 04/01/2013 - "CTR2 expression in ovarian cancer cells was inhibited by bathocuproine disulfonate, and the changes in cisplatin sensitivity were examined. "

Related Drugs and Biologics

1.	Copper
2.	Chelating Agents
3.	Cystine (L-Cystine)
4.	Cysteine (L-Cysteine)
5.	Transferrin (beta 2 Transferrin)
6.	Sulfur
7.	Sulfhydryl Compounds (Thiols)
8.	Mercaptoethanol (2 Mercaptoethanol)
9.	Iron
10.	Ions