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Azocoll

azo dye suspended in collagen of high purity

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Azo Compounds: 333
  - Azocoll: 6
Macromolecular Substances: 97
- Polymers: 13051
  - Biopolymers: 773
    - Collagen: 52417
      - Azocoll: 6
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Scleroproteins: 74
    - Extracellular Matrix Proteins: 3148
      - Collagen: 52417
        Azocoll: 6

Related Diseases

1.	Wounds and Injuries (Trauma) 11/01/1999 - "Matrix metalloproteinase (MMP) activity measured using the Azocoll assay was significantly elevated by 30 fold in chronic wounds (median 22.8 microg MMP Eq/ml) compared to acute wounds (median 0.76 microg MMP Eq/ml) (p < 0.001). " 12/01/1997 - "Wounds showed an age-related increase in MMP-2 and MMP-9 immunostaining from day 3; this was associated with degradation of gelatin as shown by zymograms and with increased proteinase activity as shown by azocoll assays. "
2.	Ocular Onchocerciasis (River Blindness) 02/01/1999 - "Studying proteolytic activity of Onchocerca volvulus (nematode causing "river blindness") shows that it is able to digest a variety of substrates such as: azoalbumine, azocoll and elastin-orcein with specific activity of 0.28, 0.57 and 1.48 mg/hour/mg of extract respectively. "
3.	Tinea (Ringworm) 09/01/1989 - "This enzyme had an optimal pH 4.5 for azocoll and was found in both isolates from tinea superficialis and granuloma trichophyticum. "
4.	Glioma (Gliomas) 04/15/1990 - "The conditioned medium (CM) of fetal human astrocytes and five glioma cell lines did not degrade azocoll in suspension, but several proteolytic activities, inhibitable by 1,10-phenanthroline, were detected on sodium dodecyl sulfate-polyacrylamide gels containing gelatin. "
5.	Burns 03/01/1962 - "1962.-An attempt has been made to correlate in vitro activities of Clostridium histolyticum H-4 proteinases, as measured against azocasein, azocoll, gelatin, and collagen, with their ability to debride full-thickness third-degree burns (360 C, 15 sec) on guinea pigs. "

Related Drugs and Biologics

1.	Gelatin
2.	Peptide Hydrolases (Proteases)
3.	Matrix Metalloproteinases (MMPs)
4.	Conditioned Culture Media
5.	Suspensions
6.	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)
7.	Enzymes
8.	Elastin
9.	Collagen
10.	azocasein