2- methyl- 3- (2,4,5- trihydroxyphenyl)alanine

RN given refers to parent cpd without isomeric designation

Also Known As:

2-methyl-3-(2,4,5-trihydroxyphenyl)alanine hydrochloride, (D-Tyr)-isomer; 2-methyl-3-(2,4,5-trihydroxyphenyl)alanine hydrochloride, (DL-Tyr)-isomer; 2-methyl-3-(2,4,5-trihydroxyphenyl)alanine hydrochloride, (L-Tyr)-isomer; 2-methyl-3-(2,4,5-trihydroxyphenyl)alanine, (L-Tyr)-isomer; MTHPA

Networked: 8 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Dearman, R J: 1 article (05/2000)
2.	Humphreys, I R: 1 article (05/2000)
3.	Kimber, I: 1 article (05/2000)
4.	Warbrick, E V: 1 article (05/2000)

Related Diseases

1.	Hypersensitivity (Allergy) 04/01/1995 - "RAST inhibition with MTHPA, MHHPA and UP-resin conjugates confirmed IgE-mediated allergy and cross-reactivity between anhydrides. " 04/01/1995 - "Both patients' immediate allergy to MTHPA and MHHPA was verified by positive prick tests to MTHPA and MHHPA, conjugated with human serum albumin (HSA), and positive radioallergosorbent tests (RASTs) to these anhydrides. " 10/01/1999 - "Methyltetrahydrophthalic anhydride (MTHPA) stimulates the production of specific IgE antibodies which can cause occupational allergy even at extremely low levels of exposure (15-22 micrograms/m3). " 09/01/1997 - "A cross sectional survey was carried out on a population of 148 workers from two condenser plants using epoxy resin with MTHPA, an acid anhydride curing agent known to cause allergy. " 05/01/2000 - "Occupational exposure to certain acid anhydrides, including trimellitic anhydride (TMA), maleic anhydride (MA), phthalic anhydride (PA), hexahydrophthalic anhydride (HHPA) and methyltetrahydrophthalic anhydride (MTHPA), has been associated with the development of respiratory allergy or asthma. "
2.	Asthma (Bronchial Asthma) 01/01/1997 - "MTHPA and HHPA can induce asthma in guinea pigs. " 04/01/1989 - "Work-associated rhinitis and asthma occurred in a subject exposed to methyl tetrahydrophthalic anhydride (MTHPA) used as a curing agent in an epoxy resin system. " 05/01/2000 - "Occupational exposure to certain acid anhydrides, including trimellitic anhydride (TMA), maleic anhydride (MA), phthalic anhydride (PA), hexahydrophthalic anhydride (HHPA) and methyltetrahydrophthalic anhydride (MTHPA), has been associated with the development of respiratory allergy or asthma. "
3.	Urticaria (Hives) 04/01/1995 - "2 workers contracted hives and itching on uncovered skin after 2 months exposure to methyltetrahydrophthalic anhydride (MTHPA) and methylhexahydrophthalic anhydride (MHHPA), to which they had airborne exposure. " 01/01/1997 - "Another type of ER hardeners are the phthalic anhydrides, such as methylhexahydrophthalic anhydride (MHHPA) and methyltetrahydrophthalic anhydride (MTHPA), which have been reported as causing immunologically-mediated respiratory diseases and contact urticaria, but not allergic contact dermatitis. "
4.	Allergic Contact Dermatitis 01/01/1997 - "Another type of ER hardeners are the phthalic anhydrides, such as methylhexahydrophthalic anhydride (MHHPA) and methyltetrahydrophthalic anhydride (MTHPA), which have been reported as causing immunologically-mediated respiratory diseases and contact urticaria, but not allergic contact dermatitis. "
5.	Bronchial Hyperreactivity 04/01/1989 - "He displayed bronchial hyperreactivity in provocation with methacholine, as well as skin prick test positivity and specific immunoglobulin E (IgE) serum antibodies, against a conjugate of MTHPA and human serum albumin. "

Related Drugs and Biologics

1.	Anhydrides
2.	methyltetrahydrophthalic anhydride
3.	Immunoglobulin E (IgE)
4.	Epoxy Resins
5.	Antibodies
6.	Acids
7.	Human Serum Albumin
8.	Methacholine Chloride (Methacholine)
9.	Pronase
10.	Phthalic Anhydrides