anemonin

a furanone dimer found in RANUNCULACEAE; do not confuse with anemonine which is 5-(carboxymethyl)-1,1-dimethylimidazolium hydroxide inner salt; ranunculine is hydrolyzed to protoanemonin which dimerizes to anemonin; structure

Networked: 10 relevant articles (3 outcomes, 2 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Chi, Chunhua: 1 article (03/2022)
2.	Hu, Dongqing: 1 article (03/2022)
3.	Jiang, Lu: 1 article (03/2022)
4.	Liu, Xiaoming: 1 article (03/2022)
5.	Lu, Meiqi: 1 article (03/2022)
6.	Wang, Lin: 1 article (03/2022)
7.	Yuan, Fang: 1 article (03/2022)
8.	Ge, Juan: 1 article (01/2019)
9.	Li, Cheng: 1 article (01/2019)
10.	Li, Tang: 1 article (01/2019)

Related Diseases

1.	Sepsis (Septicemia) 08/17/2023 - "Here, we made an investigation into the protective effects of the natural compound Anemonin (ANE) on sepsis-induced AKI both in vitro and in vivo. " 08/17/2023 - "Anemonin inhibits sepsis-induced acute kidney injury via mitigating inflammation and oxidative stress."
2.	Cerebral Infarction 06/01/2014 - "However, pretreatment with anemonin significantly reversed these levels of biochemical parameters, reduced cerebral infarct size, and improved the neurologic score in cerebral ischemic animals. "
3.	Body Weight (Weight, Body) 03/28/2022 - "Anemonin improved DSS-induced body weight loss, shortened colon length, increased DAI, and induced pathological changes in the colon tissue of mice. "
4.	Inflammation (Inflammations) 12/01/2017 - "Anemonin (ANE) is a small natural molecule extracted from various kinds of Chinese traditional herbs and has been shown to inhibiting inflammation response. " 01/01/2016 - "These findings suggest that dietary anemonin attenuates LPS-induced intestinal injury by improving mucosa restoration, alleviating intestinal inflammation and influencing TGF-β1 canonical Smads and EGFR signaling pathways." 03/01/2016 - "The results indicated that transdermal administration of anemonin is a potential modality for combating inflammation caused by RA." 03/01/2016 - "The aim of this study was to evaluate the skin permeability of anemonin, which was extracted from the Chinese herb weilingxian, and its potency of relieving the inflammation caused by rheumatoid arthritis (RA). " 03/11/2023 - "Anemonin reduces hydrogen peroxide-induced oxidative stress, inflammation and extracellular matrix degradation in nucleus pulposus cells by regulating NOX4/NF-κB signaling pathway."
5.	Brain Ischemia (Cerebral Ischemia) 06/01/2014 - "In the present study, we aimed at evaluating the potential neuroprotective effect and the underlying mechanism of anemonin against cerebral ischemia and reperfusion (I/R) injury. " 06/01/2014 - "Anemonin alleviates nerve injury after cerebral ischemia and reperfusion (i/r) in rats by improving antioxidant activities and inhibiting apoptosis pathway."

Related Drugs and Biologics

1.	Neuroprotective Agents
2.	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)
3.	Interleukin-6 (Interleukin 6)
4.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
5.	Streptozocin (Streptozotocin)
6.	Protein Kinase C
7.	Hydrogen Peroxide (Hydroperoxide)
8.	Enzymes
9.	Antioxidants

Related Therapies and Procedures

1.	Cutaneous Administration