2,3-dinor-6-ketoprostaglandin F1alpha

formed from 6-keto-PGF1alpha by Mycobacterium rhodochrous; RN given refers to (1R-(1alph,2beta(1E,3S*)))-isomer; structure given in first source

Also Known As:

2,3-DKPGF1alpha; 2,3-dinor-6-keto-PGF1alpha; 2,3-dinor-6-oxo-PGF1alpha; 2,3-dinor-6-oxoprostaglandin F1alpha; PGI2-M; cyclopentanepentanoic acid, 3,5-dihydroxy-2-(3-hydroxy-1-octenyl)-gamma-oxo-, (1R-(1 alpha,2 beta(1E,3S*),3 alpha,5 alpha))-

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Central Sleep Apnea (Central Sleep Apnea Syndrome) 11/01/1999 - "Urinary concentration of 2,3-dinor-6-keto-PGF1alpha and 2,3-dinor-TxB2 was determined, and the ratio correlated with the number of central apneas (>20s) measured in overnight polygraphy. "
2.	Vascular Diseases (Vascular Disease) 05/01/1988 - "After one week of treatment, aspirin reduced TxB2-M synthesis to a similar extent in the three groups (mean declines of 86, 84 and 78% respectively), while there was an unexpected difference in effect on PGI2-M, with only a 27% fall in the young volunteers but 53% and 54% declines in the patients with vascular disease and their age-matched controls. "
3.	Rubella (German Measles) 04/01/1997 - "The main indices studied were the fatty acid composition of the plasma, red blood cells, platelets, and adipose tissue; in vitro platelet aggregation, bleeding times, clotting factors; immune response as measured by delayed hypersensitivity skin tests, cellular proliferation of peripheral blood mononuclear cells in response to various mitogens and antigens, natural killer cell activity, and response to measles/mumps/rubella and influenza vaccines; the metabolic conversion of deuterated linoleic acid to AA and the metabolic fate of deuterated AA in the subjects on and off the high-AA diet; and the production of eicosanoids as measured by excretion of 11-DTXB2 and PGI2-M in urine. "
4.	Mumps 04/01/1997 - "The main indices studied were the fatty acid composition of the plasma, red blood cells, platelets, and adipose tissue; in vitro platelet aggregation, bleeding times, clotting factors; immune response as measured by delayed hypersensitivity skin tests, cellular proliferation of peripheral blood mononuclear cells in response to various mitogens and antigens, natural killer cell activity, and response to measles/mumps/rubella and influenza vaccines; the metabolic conversion of deuterated linoleic acid to AA and the metabolic fate of deuterated AA in the subjects on and off the high-AA diet; and the production of eicosanoids as measured by excretion of 11-DTXB2 and PGI2-M in urine. "
5.	Measles 04/01/1997 - "The main indices studied were the fatty acid composition of the plasma, red blood cells, platelets, and adipose tissue; in vitro platelet aggregation, bleeding times, clotting factors; immune response as measured by delayed hypersensitivity skin tests, cellular proliferation of peripheral blood mononuclear cells in response to various mitogens and antigens, natural killer cell activity, and response to measles/mumps/rubella and influenza vaccines; the metabolic conversion of deuterated linoleic acid to AA and the metabolic fate of deuterated AA in the subjects on and off the high-AA diet; and the production of eicosanoids as measured by excretion of 11-DTXB2 and PGI2-M in urine. "

Related Drugs and Biologics

1.	Linoleic Acid (Linoleate)
2.	Eicosanoids
3.	Thromboxane A2 (A2, Thromboxane)
4.	Epoprostenol (Prostacyclin)
5.	Mitogens
6.	Influenza Vaccines (Influenza Vaccine)
7.	Fatty Acids (Saturated Fatty Acids)
8.	Blood Coagulation Factors (Coagulation Factor)
9.	Aspirin (Acetylsalicylic Acid)
10.	Antigens