phenylalanyltryptophan

copper complex of above dipeptide inhibits gastric acid secretion; RN given refers to (L,L)-isomer

Also Known As:

Phe-Trp; phenylalanyltryptophan monoacetate, (L,L)-isomer; phenylalanyltryptophan, (D,D)-isomer; phenylalanyltryptophan, (L,D)-isomer

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

1.	Colson, Rhys N: 1 article (05/2022)
2.	Price, John T: 1 article (05/2022)
3.	Shah, Neelam: 1 article (05/2022)
4.	Sturre, Natasha P: 1 article (05/2022)
5.	Watson, Gabrielle M: 1 article (05/2022)
6.	Wilce, Jacqueline A: 1 article (05/2022)
7.	Wilce, Matthew C J: 1 article (05/2022)
8.	Yang, Xue: 1 article (05/2022)
9.	Anderson, Chris D: 1 article (01/2022)
10.	Björklund, Sebastian: 1 article (01/2022)

1.	Skin Neoplasms (Skin Cancer) 01/01/2022 - "This study leads to conclusion that due to the difficulty in quantifying less abundant Kyn, and thus the Trp/Kyn ratio, the Phe/Trp ratio might be a possible, alternative biomarker for detecting skin cancers."
2.	Visceral Pain 10/13/2016 - "In particular, the μ-agonist c[β-Ala-d-Pro-Phe-Trp] 9 was shown to elicit potent antinociception in a mouse model of visceral pain upon systemic administration."
3.	Sudden Infant Death (SID) 02/01/2017 - "When pigs were fed the DDGS-based diet, the SID of Ile, Leu, Lys, Phe, Trp, Val, and Tyr increased and then decreased (quadratic, < 0.05) during the six 2-h periods. "
4.	Pain (Aches) 01/01/2002 - "Opioidmimetics and opioid peptides containing the amino acid sequence of the message domain of endomorphins, Tyr-Pro-Phe/Trp, could exhibit unique binding activity and lead to the development of new therapeutic drugs for controlling pain."
5.	Breast Neoplasms (Breast Cancer) 05/16/2022 - "Interestingly, while the bicyclic peptide containing Phe-Trp did not display the highest affinity for Grb7-SH2 in the series, it was the most potent inhibitor of HER2+ve SKBR3 breast cancer cell migration when coupled to Penetratin. "

1.	Biomarkers (Surrogate Marker)
2.	Opioid Peptides (Opioid Peptide)
3.	Peptides (Polypeptides)
4.	Amino Acids
5.	penetratin
6.	tyrosyl-proline (Tyr-Pro)
7.	leucyl-lysine