secoverine

RN given refers to parent; structure in first source

Also Known As:

1-cyclohexyl-4-(ethyl(p-methoxy-alpha-methylphenyl)amino)-1-butanone; secoverine hydrochloride; secovorine; 1-butanone, 1-cyclohexyl-4-(ethyl(2-(4-methoxyphenyl)-1-methylethyl)amino)-

Networked: 4 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Ethylamines: 5
    - Phenethylamines: 28
      - secoverine: 4

Related Diseases

1.	Mydriasis 04/24/1981 - "Time-activity studies of secoverine and atropine were made with respect to mydriasis and oxotremorine-induced salivation, lacrimation and tremors. "
2.	Tremor (Tremors) 04/24/1981 - "Time-activity studies of secoverine and atropine were made with respect to mydriasis and oxotremorine-induced salivation, lacrimation and tremors. "
3.	Diverticular Diseases 08/01/1987 - "These studies suggest patients with diverticular disease have a similar slow wave frequency as healthy subjects, the gastrocolonic response is prolonged in patients with diverticular disease, and secoverine inhibits the colonic response." 08/01/1987 - "The gastrocolonic response in patients with diverticular disease was prolonged for 60 min. Secoverine inhibited the gastrocolonic response in patients with diverticular disease. " 08/01/1987 - "The effect of secoverine on colonic smooth muscle was measured in patients with diverticular disease and in healthy subjects. " 08/01/1987 - "Effect of secoverine on colonic myoelectric activity in diverticular disease of the colon."
4.	Irritable Bowel Syndrome (Syndrome, Irritable Bowel) 03/01/1985 - "The effect of secoverine hydrochloride on stimulated sigmoid motility: a double-blind, placebo controlled cross-over study in irritable bowel syndrome." 03/01/1985 - "The effect of oral secoverine hydrochloride on neostigmine-stimulated sigmoid motility in 12 patients with irritable bowel syndrome was studied in a double-blind placebo-controlled cross-over study. "
5.	Hypokinesia (Bradykinesia) 04/01/1991 - "Both side-effect profiles and the ability to reverse MPTP-induced hypokinesia were assessed using a variety of dopamine receptor agonists (quinpirole, PHNO, ADTN), cholinergic antagonists (scopolamine, secoverine, himbacine), a glutamate receptor antagonist (MK801) and a 5-HT receptor agonist (8-OH-DPAT). "

Related Drugs and Biologics

1.	Oxotremorine
2.	Atropine
3.	Quinpirole
4.	Excitatory Amino Acid Antagonists
5.	Cholinergic Antagonists (Anticholinergics)
6.	Dopamine Agonists (Dopamine Agonist)
7.	Dizocilpine Maleate (Dizocilpine)
8.	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)
9.	Scopolamine (Hyoscine)
10.	Serotonin Receptors