diallyl disulfide (diallyl disulphide)

05/01/2015 - "Diallyl disulfide (DADS) is characterized as an effective agent for the prevention and therapy of cancer, however, mechanisms regarding its anticancer effects are not fully clarified. "
11/01/1996 - "However, oil-soluble compounds such as diallyl disulfide are effective in reducing the proliferation of neoplasms. "
03/01/2001 - "The results of this study indicate that diallyl disulfide inhibits the growth of H-ras oncogene transformed tumors in vivo by inhibiting the membrane association of p21(H-ras) and that the allyl group may be an important determinant in the inhibitory effect of this organosulfide on tumor growth."
01/01/1998 - "The present studies reveal the antiproliferative property of diallyl disulfide (DADS) in cultured human colon tumor cells (HCT-15) relative to its ability to decrease the proportion of cells in the G1 phase and increase the proportion of cells in the G2/M phase. "
01/01/2015 - "Diallyl disulfide (DADS), a major organosulfur compound derived from garlic, has various biological properties, including anti-cancer effects. "

02/01/2015 - "Effects of diallyl disulphide on small intestinal inflammation and intestinal microbiota were also assessed. "
04/01/2015 - "Furthermore, application of an H2S-releasing molecule, diallyl disulfide (DADS), stabilized colonic HIF-1α expression, up-regulated hypoxia-responsive genes, and reduced the severity of disease during peak inflammation. "
12/01/2013 - "Diallyl-disulfide, an organosulfur compound of garlic, attenuates airway inflammation via activation of the Nrf-2/HO-1 pathway and NF-kappaB suppression."
02/01/2015 - "Diallyl disulphide co-administration dose-dependently reduced the severity of naproxen-induced small intestinal damage, inflammation and bleeding. "
03/01/2015 - "Here, we have investigated the effect of diallyl sulfide (DAS) and diallyl disulfide (DADS), two garlic-derived sulfur compounds, on intestinal inflammation in vivo as well as in intestinal isolated cells. "

07/15/2004 - "We examined the effects of diallyl disulfide (DADS), an oil-soluble organosulfur compound found in garlic, on human HepG2 hepatoma cells to better understand its effect on apoptosis and apoptosis-related genes. "
07/15/2004 - "Enhancement of diallyl disulfide-induced apoptosis by inhibitors of MAPKs in human HepG2 hepatoma cells."
08/01/1999 - "Acetylation was also induced in rat hepatoma and human breast cancer cells by diallyl disulfide or its metabolite, allyl mercaptan. "
01/01/2001 - "The present study shows that diallyl disulfide, found in garlic, is effective in inhibiting [3H]-thymidine incorporation in human hepatoma HepG2 cell cultures. "
07/01/2001 - "Induction of histone acetylation in rat liver and hepatoma by organosulfur compounds including diallyl disulfide."

02/01/2013 - "Development, characterization and efficacy of niosomal diallyl disulfide in treatment of disseminated murine candidiasis."
10/01/2010 - "These results indicate that diallyl disulphide acts as a pro-oxidant to Candida species and hence may act as a potent antifungal in the management of candidiasis."
02/01/2013 - "In the current study, a novel niosome based formulation of diallyl disulfide (DADS) was evaluated for its potential to treat disseminated candidiasis in mouse model. "

02/01/2015 - "Diallyl disulphide co-administration dose-dependently reduced the severity of naproxen-induced small intestinal damage, inflammation and bleeding. "