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aklavinone

from Streptomyces galilaeus MA 144-M1, strain 3AR-33; structure in first source

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        aklavinone: 5
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - aklavinone: 5

Experts

1.	Türker, Lemi: 1 article (01/2012)

Related Diseases

1.	Neoplasms (Cancer) 12/16/2022 - "Lastly, we tested the antiproliferative activity of the anthracyclinones in a mammalian cancer cell viability assay, in which nogalamycinone, auramycinone, and aklavinone exhibited moderate cytotoxicity against several cancer cell lines. " 01/01/2012 - "On the other hand, aklavinone is the parent aglycone of certain anthracycline antibiotics that possess anti-cancer activity too. "
2.	Cardiotoxicity 12/01/1977 - "Aclacinomycin A15), which we found in Streptomyces galilaeus MA144-M1, has aklavinone aglycone and is becoming more interesting in its low cardiac toxicity."
3.	Leukemia L1210 03/01/1982 - "3"-O-Acyl derivatives of daunomycinone, carminomycinone and aklavinone glycosides showed a marked antitumor activity against L1210 leukemia in mice with ILS 110, 86 and 86%, respectively, while 3"-O-acetyladriamycinone glycoside was highly toxic with a ILS of 44%."
4.	Dehydration (Water Stress) 03/01/1985 - "[Dehydration of aklavinone, PMR spectra of aklavinone and its dehydration products]."

Related Drugs and Biologics

1.	Anthracyclines
2.	Glycosides
3.	Anti-Bacterial Agents (Antibiotics)
4.	auramycinone
5.	daunomycinone
6.	carminomycinone
7.	aclacinomycins