L-glutamic acid-L-tyrosine copolymer

synthetic polypeptide which has suppressive effect on delayed-type hypersensitivity

Also Known As:

poly(E,Y)1-4; poly(Glu(50)Tyr(50)); poly(Glu(80)Tyr(20)); poly(Glu-Tyr)(4:1); poly(L-glutamyl-L-tyrosine)

Networked: 3 relevant articles (0 outcomes, 1 trials/studies)

1.	Alzheimer Disease (Alzheimer's Disease) 09/01/1993 - "In the present study we used 32P-labeled phosphorylase kinase and poly(Glu, Tyr) 4:1 as substrates to measure phosphoprotein phosphatase activities in Alzheimer disease and control brains. "
2.	Hyperglycemia 05/16/1988 - "Basal and insulin-stimulated insulin receptor kinase activities were also found normal for both the autophosphorylation of the beta subunit of the insulin receptor and the phosphorylation of the artificial substrate poly (Glu-Tyr) 4:1. Thus, in that model of chronic insulin deficiency and mild hyperglycemia: 1) liver insulin receptors are not up-regulated; 2) tyrosine kinase activity remains unaffected. "
3.	Carcinoma (Carcinomatosis) 07/24/1991 - "Protein tyrosine kinase (PTK) activities in methyl nitrosourea (MNU)-induced rat mammary carcinoma has been investigated by using poly (glu: tyr; 4:1) as an exogenous substrate. "

1.	Phosphorylase Kinase (Phosphorylase Kinase, Glycogen)
2.	Phosphoprotein Phosphatases (Phosphatases, Protein)
3.	Protein-Tyrosine Kinases (Tyrosine Kinase)
4.	Insulin Receptor
5.	Phosphotransferases (Kinase)
6.	Insulin (Novolin)