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19-noraldosterone

Also Known As:

19-Norpregn-4-en-18-al, 11,21-dihydroxy-3,20-dioxo-, (11beta)-

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Aldosterone: 11485
        19-noraldosterone: 6
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Adrenal Cortex Hormones: 62914
    - Hydroxycorticosteroids: 7
      - 11-Hydroxycorticosteroids: 56
        Aldosterone: 11485
        19-noraldosterone: 6

Experts

1.	Demura, Masashi: 1 article (06/2002)
2.	Furukawa, Kenji: 1 article (06/2002)
3.	Mabuchi, Hiroshi: 1 article (06/2002)
4.	Takeda, Yoshiyu: 1 article (06/2002)
5.	Usukura, Mikiya: 1 article (06/2002)
6.	Yoneda, Takashi: 1 article (06/2002)

Related Diseases

1.	Adenoma (Adenomas) 01/01/1995 - "Urinary excretion of 19-noraldosterone, 18,19-(OH)2-B, and 18-OH-19-nor-B were increased in patients with aldosterone-producing adenoma (APA) and in those with idiopathic hyperaldosteronism (IHA), but the two did not differ significantly. " 06/01/1992 - "In patients with idiopathic hyperaldosteronism, urinary 19-noraldosterone (207 +/- 51 pmol/day), 18, 19(OH)2-B (21 +/- 4.2 nmol/day) and 18-OH-19-nor-B (879 +/- 213 pmol/day) levels were lower but not significantly different from 19-noraldosterone (263 +/- 56 pmol/day), 18, 19(OH)2-B (40 +/- 8.7 nmol/day) and 18-OH-19-nor-B (1322 +/- 267 pmol/day) seen in patients with aldosterone-producing adenoma. " 06/01/1993 - "In the present study we demonstrate the in vitro formation of 18-deoxy-19-noraldosterone from 19-noraldosterone in a human aldosterone-producing adenoma and normal adrenal tissue. " 06/01/1992 - "Urinary excretion of 19-noraldosterone, 18, 19-dihydroxycorticosterone and 18-hydroxy-19-norcorticosterone in patients with aldosterone-producing adenoma or idiopathic hyperaldosteronism."
2.	Stroke (Strokes) 12/01/1995 - "Urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat and stroke-prone spontaneously hypertensive rat." 01/01/1995 - "In spontaneously hypertensive rats (SHR) and stroke-prone SHR (SHRSP), urinary 19-noraldosterone was increased at the prehypertensive stage compared with Wistar-Kyoto (WKY) rats. " 12/01/1995 - "1. We measured the urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat (SHR) and stroke-prone SHR (SHRSP) during the development of hypertension and compared these measurements with Wistar-Kyoto (WKY) rats. "
3.	Hypertension (High Blood Pressure) 01/01/1995 - "These elevated levels of 19-noraldosterone may contribute to hypertension in some individuals and in experimental hypertensive rats." 12/01/1995 - "1. We measured the urinary excretion of 19-noraldosterone in the spontaneously hypertensive rat (SHR) and stroke-prone SHR (SHRSP) during the development of hypertension and compared these measurements with Wistar-Kyoto (WKY) rats. " 01/01/1995 - "Significance of 19-noraldosterone, a new mineralocorticoid, in clinical and experimental hypertension."
4.	Hyperaldosteronism (Conn Syndrome) 01/01/1995 - "Though urinary 18-OH-F and 18-OH-B concentrations were useful markers, urinary 19-noraldosterone, 18,19-(OH)2-B, and 18-OH-19-nor-B could not be used to distinguish the two subsets of primary aldosteronism. " 01/01/1995 - "Urinary excretion of 19-noraldosterone, 18,19-(OH)2-B, and 18-OH-19-nor-B were increased in patients with aldosterone-producing adenoma (APA) and in those with idiopathic hyperaldosteronism (IHA), but the two did not differ significantly. " 06/01/1992 - "In patients with idiopathic hyperaldosteronism, urinary 19-noraldosterone (207 +/- 51 pmol/day), 18, 19(OH)2-B (21 +/- 4.2 nmol/day) and 18-OH-19-nor-B (879 +/- 213 pmol/day) levels were lower but not significantly different from 19-noraldosterone (263 +/- 56 pmol/day), 18, 19(OH)2-B (40 +/- 8.7 nmol/day) and 18-OH-19-nor-B (1322 +/- 267 pmol/day) seen in patients with aldosterone-producing adenoma. " 06/01/1992 - "Though urinary 18-OH-F and 18-OH-B concentrations were useful markers, the mineralocorticoid steroids which we can only now measure, 19-noraldosterone, 18, 19(OH)2-B and 18-OH-19-nor-B, could not be used to distinguish the two subsets of primary aldosteronism." 06/01/1992 - "Urinary excretion of 19-noraldosterone, 18, 19-dihydroxycorticosterone and 18-hydroxy-19-norcorticosterone in patients with aldosterone-producing adenoma or idiopathic hyperaldosteronism."
5.	Pregnancy-Induced Hypertension (Hypertension, Pregnancy Induced) 06/01/2002 - "19-Noraldosterone in pregnancy-induced hypertension."

Related Drugs and Biologics

1.	Aldosterone
2.	19-norcorticosterone
3.	Mineralocorticoids
4.	Steroids
5.	18-hydroxy-19-norcorticosterone