4-tolylurea

Also Known As:

p-tolylurea

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

1.	Carcinogenesis 06/01/1980 - "Carcinogenesis bioassay of acetamide, hexanamide, adipamide, urea and P-tolylurea in mice and rats."
2.	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 04/26/2012 - "Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo."
3.	Neoplasms (Cancer) 06/01/1980 - "In male mice treated with acetamide (low dose, 7/50; high dose, 7/46); hexanamide (low dose, 6/35; high dose, 6/39); and p-tolylurea (10/43), there was a compound-related increase in hematopoietic tumors, namely malignant lymphomas. "
4.	Lymphoma (Lymphomas) 06/01/1980 - "In male mice, acetamide, hexanamide, and p-tolylurea caused malignant lymphomas. " 06/01/1980 - "In male mice treated with acetamide (low dose, 7/50; high dose, 7/46); hexanamide (low dose, 6/35; high dose, 6/39); and p-tolylurea (10/43), there was a compound-related increase in hematopoietic tumors, namely malignant lymphomas. "