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mepregenol diacetate

tested for use in combination with ethinyl estradiol; RN given refers to (3beta)-isomer

Also Known As:

6-methylpregna-4,6-dien-3 beta,17 alpha-diol-20-one diacetate; acetomepregenol

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

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Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnadienes
        Pregnadienediols
        mepregenol diacetate: 3

Related Diseases

1.	Habitual Abortion (Recurrent Miscarriage) 06/01/1989 - "Monitoring for pregnancy development and treatment efficacy in 104 females treated with acetomepregenol for threatened recurrent abortion at 8 to 16 week of gestation was performed with the use of ultrasonic variations. " 06/01/1989 - "Therapeutic efficacy of acetomepregenol (synthetic progestogen) was evaluated in 104 women (average age was 28.3 years) with threatened habitual abortion at 7-16 weeks of gestation. "
2.	Spontaneous Abortion (Miscarriage) 06/01/1989 - "[Acetomepregenol in the treatment of threatened late miscarriages (clinico-experimental study)]." 06/01/1989 - "[Use of acetomepregenol in the treatment of threatened habitual miscarriage]." 06/01/1989 - "Of 104 women treated with acetomepregenol during the 1st trimester, 87 gave birth to normal babies, 8 had miscarriage at 12-27 weeks of gestation, and 9 had premature labor. "
3.	Pain (Aches) 06/01/1989 - " Acetomepregenol was given not earlier than 7-8 weeks of gestation in a daily dose of 0.5-1.5 mg. Total dose per course was 10-45 mg; daily dose was gradually tapered off to 0.26-0.125 mg. During the treatment, 77.9% of the patients showed alleviation or complete disappearance of pain (on day 2-4), 87.5% showed normalization of urinary chorionic gonadotropin levels (1.5-2 weeks after the onset of treatment), and 88.6% showed normalization of the basal temperature (on day 5-7). "
4.	Neoplasms (Cancer) 01/01/1997 - "Antitumor effect on hormone dependent tumors has been demonstrated following oral and parenteral treatment of mice and rats with a gestagenic drug -- acetomepregenol."
5.	Nausea 06/01/1989 - " The only side-effect of acetomepregenol was nausea recorded in 24% of the patients."

Related Drugs and Biologics

1.	Progestins (Progestagens)
2.	Hormones (Hormone)
3.	Chorionic Gonadotropin (Human Chorionic Gonadotropin)