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5- (3,4- dihydroxy- 1,5- cyclohexadien- 1- yl)- 5- phenylhydantoin
metabolite of phenytoin; RN given refers to cpd without isomeric designation
Also Known As:
5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin, (3R-(1(R*),3alpha,4beta))-isomer; 5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin, (3R-(1(S*),3alpha,4beta))-isomer; 5-DCYPH
Networked:
1
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Azoles: 2138
Imidazoles: 150
Imidazolidines: 39
Hydantoins: 306
Phenytoin: 5446
5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin: 1
Related Diseases
1.
Dehydration (Water Stress)
01/01/1979 - "
A routine gas chromatographic assay for urinary 5-(4-hydroxyphenyl)-5-phenylhydantoin (p-HPPH), the major metabolite of phenytoin (PHT) in man, was adapted to allow quantitation of 5-(3,4-dihydroxy-1,5-cyclohexadien-1-yl)-5-phenylhydantoin (Dihydrodiol, DHD) is based on the observation that acid-catalyzed dehydration of DHD quantitatively yields a mixture of p-HPPH and m-HPPH in a reproducible molar ratio of 56:44p-HPPH: m-HPPH and on the assumption that all m-HPPH found in urine after heating with acid has been derived from DHD.
"
Related Drugs and Biologics
1.
Phenytoin (Dilantin)
2.
Acids
3.
trans-1,2-dihydro-1,2-naphthalenediol
4.
2-(1-hexyloxyethyl)-2-devinyl pyropheophorbide-a (HPPH)
5.
hydroxyphenytoin