benzo(e)pyrene

02/01/1980 - "The tumor-initiating activities of benzo(e)pyrene and several of its derivatives were determined on the skin of female CD-1 mice. "
02/01/1980 - "The tumorigenic activities of benzo(e)pyrene and several of its derivatives were determined in two mouse tumor models. "
08/01/1984 - "Benzo[e]pyrene (B[e]P), a weakly carcinogenic polycyclic aromatic hydrocarbon (PAH) modifies tumor induction in mouse skin and the induction of mutation in mammalian cells by carcinogenic PAH. "
09/01/1983 - "Benzo[e]pyrene and benzo[ghi]perylene showed no tumor-producing effect in this system when given at doses of 5 mg. The histologic and mathematical evaluations indicated that the investigated compounds had distinct carcinogenic potencies. "
01/01/1982 - "In the present study, we have examined the effects of benzo[e]pyrene (B[e]P) and dibenz[a,c]anthracene (DB[a,c]A) on the skin tumor-initiating activities of methylated and non-methylated polycyclic aromatic hydrocarbons (PAH). "

04/01/1993 - "Benzo(e)pyrene (B(e)P) promotes carcinogenesis in the skin. "
07/15/1987 - "Benzo(e)pyrene [B(e)P] cotreatment slightly increases the tumor-initiating activity of benzo(a)pyrene [B(a)P] and greatly decreases the tumor-initiating activity of 7,12-dimethylbenz(a)anthracene (DMBA) in Sencar mice (DiGiovanni et al., Carcinogenesis 3: 371-375, 1982). "
03/01/1995 - "Potential genoprotective role for UDP-glucuronosyltransferases in chemical carcinogenesis: initiation of micronuclei by benzo(a)pyrene and benzo(e)pyrene in UDP-glucuronosyltransferase-deficient cultured rat skin fibroblasts."
09/01/1993 - "In the present study, we have exposed in vivo the xenotransplanted immortalized human bronchial epithelial cell line BEAS-2B to the ultimate carcinogen of B[a]P, benzo[a]pyrene diolepoxide (BPDE), to DNP or to the benzo[e]pyrene, a less active compound that has tumor-promoting abilities in mouse skin carcinogenesis bioassays. "

09/01/1994 - "Hepa 1c1c7 (WT), TAOc1BPrc1 (CI), and BPrc1 (CII) mouse hepatoma cells were exposed to benzo[e]pyrene (B[e]P) or benzo[a]pyrene (B[a]P). "
01/01/1992 - "Induction of CYP1A1 gene expression in H4-II-E rat hepatoma cells by benzo[e]pyrene."
05/01/2007 - "The transcription factor NF-kappaB was activated only in the hepatoma 27 cells by BP treatment but not by its noncarcinogenic isomer benzo[e]pyrene (BeP). "
01/01/1992 - "In this study, we used the PAH isomers benzo[a]pyrene (BaP) and benzo[e]pyrene (BeP) to further evaluate the role of the 4S PAH-binding protein in induction of the CYP1A1 gene in H4-II-E rat hepatoma cells. "
09/01/1994 - "Induction of CYP1A1 gene expression in mouse hepatoma cells by benzo[e]pyrene, a ligand of the 4S polycyclic hydrocarbon-binding protein."

09/14/1984 - "The results of the present and previous studies suggest that the polycyclic aromatic hydrocarbons (excluding benzo[e]pyrene) may be the only potential atherogens in avian atherosclerosis. "
09/14/1984 - "Benzo[e]pyrene and 2,4,6-trichlorophenol were ineffective in the induction or enhancement of atherosclerosis in the pigeons. "

05/01/2023 - "Benzo[A]Pyrene and Benzo[E]Pyrene: Photoreactivity and Phototoxicity toward Human Keratinocytes."
02/01/1976 - "The following results were obtained: 1. Phototoxicity for ciliates of the highly carcinogenic benzo(a)pyrene may still be demonstrated in dilutions containing but 2 ppb (mug/l) of the substance, while the non-carcinogenic benzo(e)pyrene and fluorenthene are only weakly toxic in much higher concentrations. "