virotoxins

monocyclic toxic peptides found in Amanita virosa mushrooms; main component viroisin; similar in structure to phallatoxins; general structure in first source; see also records for viroidin & viroisin

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Macrocyclic Compounds: 15
  - Cyclic Peptides: 530
    - virotoxins: 5
Amino Acids, Peptides, and Proteins: 1
- Peptides: 82426
  - Cyclic Peptides: 530
    - virotoxins: 5

Experts

1.	Huang, Sheng-He: 1 article (11/2017)
2.	Jong, Ambrose: 1 article (11/2017)
3.	Li, Li: 1 article (11/2017)
4.	Liu, Lingjuan: 1 article (11/2017)
5.	Liu, Liqun: 1 article (11/2017)
6.	Mao, Ding-An: 1 article (11/2017)
7.	Wu, Chun-Hua: 1 article (11/2017)
8.	Yu, Jingyi: 1 article (11/2017)
9.	Zhang, Bao: 1 article (11/2017)
10.	Purohit, Vishnudutt: 1 article (09/2014)

Related Diseases

1.	Necrosis 03/01/1982 - "Virotoxins A and B are toxic compounds which produce hemorrhagic necrosis of liver that have been observed in detail by electron microscopy. " 12/01/1985 - "The virotoxins and phalloidin induced hemorrhagic necrosis of the liver. "
2.	Substance-Related Disorders (Drug Abuse) 11/01/2017 - "One of the most challenging issues in HIV-associated neurocognitive disorders (HAND) caused by HIV-1 virotoxins and drug abuse is the lack of understanding the underlying mechanisms that are commonly associated with disorders of the blood-brain barrier (BBB), which mainly consists of brain microvascular endothelial cells (BMEC). "
3.	Neurocognitive Disorders (Clerambault Syndrome) 11/01/2017 - "One of the most challenging issues in HIV-associated neurocognitive disorders (HAND) caused by HIV-1 virotoxins and drug abuse is the lack of understanding the underlying mechanisms that are commonly associated with disorders of the blood-brain barrier (BBB), which mainly consists of brain microvascular endothelial cells (BMEC). "
4.	Inflammation (Inflammations) 09/01/2014 - "Down regulation of inflammation by CB2 activation is mediated through blunted activation of peri vascular macrophages and microglia; decreased production of tumor necrosis factor-α, chemokines and virotoxins. "
5.	Dementia (Dementias) 05/12/2000 - "Thus, like other virotoxins, it is shown for the first time that nef may also contribute to neuronal damage that has been reported in dementia in late HIV disease."

Related Drugs and Biologics

1.	Chemokines
2.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
3.	Phalloidine