anti-IgE

12/01/2004 - "Current work has documented a marked decrease in tissue eosinophils, lymphocytes, and interleukin-4-positive cells by anti-IgE treatment and has provided insight into the mechanisms underlying improved control of asthma. "
01/01/2012 - "Anti-IgE therapy is beneficial in selected patients with severe asthma. "
08/01/2006 - "Following administration of anti-IgE monoclonal antibody she experienced significant improvement in her asthma control"
01/01/2014 - "For many years, pathogenetic concepts and the results of clinical trials supported the view that anti-IgE treatment is specifically effective in allergic asthma. "
04/01/2013 - "Anti-IgE therapy can be effective in non-atopic severe asthma."

01/01/2015 - "Herein, we present two cases of patients with severely limited expressive language , in whom we observed marked improvement in behavioral symptoms and even cognitive activity following control of their symptoms of allergic rhinitis with the use of omalizmab, a humanized anti-IgE antibody. "
05/01/2000 - "Anti-IgE therapy offers protection against allergen-induced bronchoconstriction and reduces severity of symptoms of allergic rhinitis. "
01/01/1993 - "[Study on basophil releasability induced by anti-IgE in allergic rhinitis]."
12/01/2015 - "The aim of this review is to provide an update on current findings on immunological and clinical effects of allergen immunotherapy and anti-IgE therapy, which have been shown to have synergistic modes of action for the treatment of allergic rhinitis. "
01/01/2009 - "Treatment of allergic rhinitis with anti-IgE has been shown to be safe and to reduce specific symptoms. "

11/01/2015 - "Basophil sensitivity may be used to monitor patients on allergen immunotherapy, anti-IgE treatment or in the natural resolution of allergy. "
01/01/2015 - "CD63 peanut/anti-IgE and CD-sens values can be used to estimate the severity and threshold of allergic reactions during OFCs."
01/01/2015 - "The ratio of the percentage of CD63(+) basophils after stimulation with peanut and after stimulation with anti-IgE (CD63 peanut/anti-IgE) was independently associated with severity (P = .001), whereas the basophil allergen threshold sensitivity CD-sens (1/EC₅₀ × 100, where EC₅₀ is half maximal effective concentration) value was independently associated with the threshold (P = .020) of allergic reactions to peanut during OFCs. "
01/01/2014 - "A panoply of critical issues and suggestive advances have rendered this assay a promising yet puzzling tool to endeavor a full comprehension of innate immunity of allergy desensitization and manage allergen or monoclonal anti-IgE therapy. "
07/01/2011 - "This novel anti-IgE DARPin-Fc fusion protein might represent a potential drug candidate for preventive or immediate treatment of allergic reactions."

01/01/2006 - "Anti-IgE monoclonal antibody is the first potential therapy for food allergy that is under-going testing in clinical trials."
01/01/2014 - "This review focuses on non-allergen specific (anti-IgE, Chinese herbal formula, etc..) and allergen specific treatments for food allergy. "
12/01/2003 - "Response to "effect of anti-IgE therapy in patients with food allergy"."
08/01/2003 - "Effect of anti-IgE therapy in patients with food allergy."
07/01/2003 - "In food allergy patients, the density of eosinophils, the presence of intraepithelial eosinophils, and the rate of degranulation showed a highly significant correlation to the initial basal release of ECP by mucosal tissue (Kendall tau = 0.619, 0.381, and 0.609, respectively; p < 0.05 for all) but not to their capability to be stimulated with anti-IgE. "

06/01/2006 - "A trial of anti-IgE resulted in complete resolution of her urticaria and its associated manifestations. "
04/01/2005 - "Although it has been shown that basophils from patients with chronic ordinary urticaria (CU) are less responsive than normal basophils when stimulated with anti-IgE, very few studies have examined the response of those cells to alternative stimuli. "
09/01/2015 - "Anti-IgE for chronic urticaria - are children little adults after all?"
05/01/2015 - "Therefore, serum testing for anti-IgE receptor Ab is required to identify this subgroup of chronic urticaria patients."
05/01/2015 - "Totally, 438 patients with a clinical presentation of chronic urticaria (2011-2013) had anti-IgE receptor Ab tested and 37 of those patients had skin biopsy. "