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dihydro-5-azaorotic acid
Also Known As:
5-aza-5,6-dihydroorotic acid; DHOX; dihydrooxonate
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
1-Ring Heterocyclic Compounds
Pyrimidines: 510
Pyrimidinones: 71
Uracil: 1493
Orotic Acid: 384
dihydro-5-azaorotic acid: 2
Heterocyclic Acids
Orotic Acid: 384
dihydro-5-azaorotic acid: 2
Related Diseases
1.
Hepatocellular Carcinoma (Hepatoma)
01/01/1988 - "
The results demonstrate that cytidine levels modulate the inhibitions of hepatoma colony formation by both PALA and DHOX and that co-administration of these drugs together with cytidine provides a simple expedient to increase drug efficacy.
"
2.
Ehrlich Tumor Carcinoma
01/01/1980 - "
In order to elucidate the role of this oxygen-dependent anabolic process in the arrest of cell proliferation under anaerobic culture conditions, the effect of the antimetabolite dihydro-5-azaorotic acid on growth, metabolism and cell cycle distribution of Ehrlich ascites tumor cells was studied and compared with the effect of oxygen-free culture conditions.
"
Related Drugs and Biologics
1.
Oxygen (Dioxygen)
2.
Cytidine
3.
Antimetabolites
4.
sparfosic acid (PALA)