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bis(dinitrophenyl)lysine
Also Known As:
di-DNP-lysine; L-Lysine, N(2),N(6)-bis(2,4-dinitrophenyl)-
Networked:
5
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Amino Acids, Peptides, and Proteins: 1
Amino Acids: 30675
Essential Amino Acids: 1152
Lysine: 6737
bis(dinitrophenyl)lysine: 5
Basic Amino Acids: 178
Lysine: 6737
bis(dinitrophenyl)lysine: 5
Diamino Amino Acids: 101
Lysine: 6737
bis(dinitrophenyl)lysine: 5
Related Diseases
1.
Anaphylaxis (Anaphylactic Shock)
12/01/1989 - "
Animals that received di-DNP-lysine underwent anaphylaxis and were observed to have significantly greater serum concentrations of immunoreactive OVA (iOVA) than control mice.
"
01/01/1992 - "
These findings indicate that enhanced microvascular permeability occurs during two phases in actively immunized guinea pigs challenged topically with di-DNP-lysine and that these phases correspond to the clinical signs that constitute the EPR and LPR of ocular anaphylaxis.
"
12/01/1989 - "
The severity of anaphylaxis, which varied with the dose of di-DNP-lysine administered, influenced the uptake of OVA; greater amounts of iOVA were detected in serum of mice undergoing more severe anaphylaxis.
"
04/01/1990 - "
The capacity of the stomach to participate in anaphylaxis induced by the hapten N,N'-di-2,4,dinitrophenyllysine (di-DNP-lysine) was examined in BDF1 female mice immunized with dinitrophenylated Ascaris suum extract.
"
12/01/1989 - "
Di-DNP-lysine is a synthetic hapten that reliably induced anaphylaxis in sensitized animals challenged by gavage.
"
2.
Edema (Dropsy)
04/01/1990 - "
Gastric tissue sections from immunized mice challenged orally or intravenously with di-DNP-lysine showed compaction of erythrocytes in blood vessels, degranulation of mast cells, degenerative changes in the gastric epithelium, expulsion of mucus from gastric glands, and edema in the lamina propria.
"
02/01/1990 - "
Only di-DNP-lysine elicited clinical signs of redness, edema, and tearing and histologic evidence of mast cell degranulation.
"
02/01/1987 - "
Clinical conjunctival edema and histologic mast cell degranulation increased with higher concentration of di-DNP-lysine.
"
3.
Wounds and Injuries (Trauma)
04/01/1990 - "
Following wound closure, animals were gavage-fed ovalbumin together with di-DNP-lysine.
"
Related Drugs and Biologics
1.
Haptens
2.
Ovalbumin
Related Therapies and Procedures
1.
Intravenous Injections