EDDA (NiEDDA)

RN given refers to parent cpd

Also Known As:

NiEDDA; EDDA Copper salt; EDDA disodium salt; EDDA monosodium salt; EDDA-Zn; EDDA-maganeese; Fe(III)-EDDA; Fe(III)-ethylenediamine-N,N'-diacetate; N,N'-ethylenediaminediacetic acid; iron(2+)-EDDA; zinc-EDDA

Networked: 117 relevant articles (11 outcomes, 32 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Polyamines: 3918
    - Diamines: 518
      - Ethylenediamines: 7
        Edetic Acid: 3051
        EDDA: 117
- Carboxylic Acids: 973
  - Acyclic Acids
    - Acetates: 4994
      - Edetic Acid: 3051
        EDDA: 117

Experts

1.	Mikołajczak, Renata: 12 articles (01/2016 - 01/2004)
2.	Ferro-Flores, Guillermina: 10 articles (01/2018 - 07/2006)
3.	Abedi, Seyed Mohammad: 8 articles (01/2020 - 02/2014)
4.	Hosseinimehr, Seyed Jalal: 7 articles (09/2021 - 02/2014)
5.	Rzeszutek, Katarzyna: 7 articles (09/2006 - 01/2004)
6.	Erfani, Mostafa: 6 articles (01/2022 - 04/2013)
7.	Mikolajczak, Renata: 6 articles (01/2020 - 04/2004)
8.	Kozak, Józef: 6 articles (09/2006 - 01/2004)
9.	Kuśmierek, Jacek: 6 articles (09/2006 - 01/2004)
10.	Płachcińska, Anna: 6 articles (09/2006 - 01/2004)

Related Diseases

1.	Neoplasms (Cancer) 06/29/2023 - "Imaging and ex vivo biodistribution studies in LNCaP tumor-bearing mice showed that [99mTc]Tc-EDDA/HYNIC-iPSMA and the three novel tracers successfully visualized LNCaP tumor xenografts in SPECT images and were excreted mainly via the renal pathway. " 01/01/2023 - "[99mTc][Tc-HYNIC/EDDA]-Met(O) revealed magnificent tumor uptake at early time points, with 1.98 ± 0.33 % injected activity per gram tumor (% IA/g) at 30 min post injection. " 01/01/2020 - "More recently, 99mTc-EDDA/HYNIC-TOC(Tektrotyd®) was introduced into the market and its use has been approved for imaging of patients with L-NETs and other SSTR-positive tumors. " 12/01/2013 - "Semiquantitative analysis showed higher tumor/organ count ratios for both whole-body and SPECT (99m)Tc- EDDA/HYNIC-Octreotate scans. " 05/01/2008 - "A real-time interactive pulmonary nodule analysis system for chest DR image softcopy reading (IQQA-Chest; EDDA Technology, Princeton Junction, NJ) was used in daily practice with a Picture Archiving and Communication System in a National Cancer Institute-designated cancer teaching hospital. "
2.	Solitary Pulmonary Nodule 10/01/2004 - "Efficacy of 99mTc-EDDA/HYNIC-TOC scintigraphy in differential diagnosis of solitary pulmonary nodules." 09/01/2006 - "The aim of the study was to determine an optimal method for the evaluation of scintigrams obtained with (99m)Tc-EDDA/HYNIC-TOC for the purpose of differential diagnosis of solitary pulmonary nodules (SPNs) and to assess the diagnostic value of the method. " 09/01/2006 - "Differential diagnosis of solitary pulmonary nodules based on 99mTc-EDDA/HYNIC-TOC scintigraphy: the effect of tumour size on the optimal method of image assessment." 02/01/2006 - "A simple method, of quantitatively assessing 99mTc-EDDA/HYNICTOC uptake in solitary pulmonary nodules by means of a T/B ratio can play a role that is complementary to the visual evaluation of scintigrams. " 02/01/2006 - "Short communication: Semiquantitative assessment of 99mTc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodules--a complementary role to visual analysis."
3.	Neoplasm Metastasis (Metastasis) 01/01/2012 - "The aim of this research was to determine the validity in terms of specificity, sensitivity, and the agreement beyond chance with the biopsy (gold standard) of the ⁹⁹mTc-EDDA-HYNIC-Tyr³octreotide (⁹⁹mTc-TOC) to image and localize NETs and their metastases. " 01/01/2016 - "SPECT-CT studies with 99mTc-EDDA/HYNIC-TOC resulted in exact pre-surgical and pre-treatment N/M staging of bronchial and thymic NETs, except 2 cases with multiple hepatic metastases and 1 with massive suprarenal metastasis. " 01/01/2018 - "We present an 82-year-old female, in whom an asymptomatic cerebellar metastasis from PTC was diagnosed by means of Tc-99m-EDDA/HYNIC-TOC scintigraphy four years after the initial diagnosis. " 10/01/2006 - "99mTc-EDDA/HYNIC-octreotate WB scans revealed more metastases than 111In-Octreoscan, with better individual separation. " 10/01/2006 - "High-quality 99mTc-EDDA/HYNIC-octreotate images were obtained in all cases, with maximum tumour tracer accumulation 4 h p.i. The mean target/non-target ratios for whole body (WB) and SPECT scans were, respectively, as follows: primary lesions: 4.5 and 10.2; metastases: liver, 3.1 and 12.3; abdominal focal lesions, 2.7 and 5.8; lung, 2.7 and 8.3; mediastinum, 3.4 and 7.6; bones, 6.8 and 19.0. "
4.	Graves Ophthalmopathy 01/01/2012 - "Efficacy of (99m)Tc-EDDA/HYNIC-TOC SPECT/CT scintigraphy in Graves' ophthalmopathy." 01/01/2012 - "The aim of this study was to investigate the predictive role of the orbital somatostatin receptor scintigraphy with (99m)Tc-EDDA/HYNIC-TOC ((99m)Tc-TOC) to detect clinical stage of Graves' ophthalmopathy and the response to corticosteroid therapy. "
5.	Pulmonary Tuberculosis 12/01/2014 - "Tc-EDDA-tricine-HYNIC-Tyr-octreotate scintigraphy may help to differentiate between active and inactive pulmonary tuberculosis. " 12/01/2014 - "The current study was performed to evaluate the impact of Tc-EDDA-tricine-HYNIC-Tyr-octreotate in the differentiation of active from inactive pulmonary tuberculosis lesions. "

Related Drugs and Biologics

1.	tricine
2.	Peptides (Polypeptides)
3.	Ligands
4.	Somatostatin Receptors (Somatostatin Receptor)
5.	Octreotide (Sandostatin)
6.	Radiopharmaceuticals
7.	99mTc-octreotide
8.	Radioisotopes (Radionuclides)
9.	Proteins (Proteins, Gene)
10.	Integrin beta3 (GPIIIa)

Related Therapies and Procedures

1.	Therapeutics
2.	Radiotherapy
3.	Gamma Cameras (Gamma Camera)
4.	Intravenous Injections
5.	Injections