CB 3703

inhibitor of dihydrofolate reductase & thymidylate synthetase; RN given refers to parent cpd

Also Known As:

CB 3703 disodium salt; CB-3703; N-(p-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-L-glutamic acid; L-glutamic acid, N-(4-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Quinazolines: 402
      - CB 3703: 1

Related Diseases

1.	Carcinoma (Carcinomatosis) 07/01/1984 - "Quinazoline CB 3717 and CB 3703 inhibition of folate retention and metabolism in Ehrlich ascites carcinoma cells and some organs of the host-mouse."
2.	Ascites 07/01/1984 - "Quinazoline CB 3717 and CB 3703 inhibition of folate retention and metabolism in Ehrlich ascites carcinoma cells and some organs of the host-mouse."

Related Drugs and Biologics

1.	Quinazolines
2.	Folic Acid (Vitamin M)
3.	CB 3717