bleomycetin

07/01/2014 - "The aim of the present study was to determine the molecular mechanism(s) underlying the therapeutic effects of pingyangmycin against infantile hemangiomas. "
01/01/2013 - "[Therapeutic mechanism of bleomycin A5 on infancy hemangioma: an experimental study]."
12/01/2015 - "Pingyangmycin (PYM), a glycopeptide antibiotic, has been recommended as a stand treatment for hemangioma. "
07/01/2014 - "The data demonstrated that the pro‑apoptotic activity of pingyangmycin against infantile hemangiomas involves p53 pathway activation. "
07/01/2014 - "Pingyangmycin stimulates apoptosis in human hemangioma-derived endothelial cells through activation of the p53 pathway."

01/01/2004 - "This was to study the signal transduction pathways that might exert the apoptotic effects of bleomycin A5 on tumor cells, as well as to examine the possibility of lower dosing of such drug in combinative treatment with other compounds in vitro. "
08/01/2014 - "The low concentrations of pingyangmycin was injected in 18 cases, and Phase II surgical resection was performed in 6 cases after 6 months, because of the large tumors and a wide range of invasion. "
07/01/2006 - "The results indicated that the external carotid artery embolization with Pingyangmycin-loaded ox-dex-GMs at reduced dosages prolonged the local drug concentration at a higher level, and could achieve the purpose of a localized targeting tumor therapy. "
01/01/2004 - "Previous work has shown that bleomycin A5 exerts its apoptotic effects on tumor cells. "
05/01/1995 - "Pingyangmycin as a 99mTc carrier in tumor localization."

07/01/1993 - "[Cytotoxicity of lymphokine-activated killer cells in conjunction with pingyangmycin to human tongue carcinoma (Tca8113) in vitro and vivo]."
12/01/1980 - "The antitumor effect of bleomycetin on Ehrlich's carcinoma was somewhat less pronounced. "
08/01/2005 - "After 8 mg of Pingyangmycin infused, the patients were treated with microwave hyperthermia at 43 degrees C for 40 min. The part of carcinoma tissue was removed with surgical operations at before treatment and aftre five times of treatment. "
10/01/2006 - "The results suggested the chemotherapeutic sensitivity of Tca8113 carcinoma cell to Pingyangmycin was improved by the inhibition of NF-kappaB/p65 signal transduction."
03/01/1989 - "During 1984-1986, fifty-one patients, including 42 squamous cell carcinomas, 8 carcinomas of salivary gland origin and 1 malignant histiocytoma, were treated in our hospital using the PVP (CDDP, VCR and PINGYANGMYCIN) regimen or single CDDP. "

06/01/2013 - "To evaluate the safety and efficacy of intralesional pingyangmycin for treatment of orbital vascular malformations. "
10/01/2009 - "[The clinical study of using Pingyangmycin of high concentration to treat vascular malformation in oral and maxillofacial region]."
12/10/2014 - "Pingyangmycin (PYM) is an effective drug to treat vascular malformations (VM), but can easily diffuse from the injection site, which will reduce its therapeutic effect and increase side effect. "
04/01/2010 - "Concentration is more important than dose when using intralesional Pingyangmycin injection for treatment of vascular malformations."
10/01/2009 - "To evaluate the clinical effect of using high concentration Pingyangmycin to treat vascular malformation in oral and maxillofacial region. "

06/01/2001 - "Pingyangmycin is a better sclerosant for the therapy of cavernous hemangioma."
10/01/2000 - "Injection of Pingyangmycin is selective primary method for cavernous and strawberry hemangioma treatment."
09/01/1994 - "[Treatment of maxillofacial cavernous hemangioma with pingyangmycin]."
06/01/2001 - "The aim of this study was to investigate the mechanism of Pingyangmycin sclerotherapy for cavernous hemangiomas. "
12/01/2001 - "Intralesional injection of Pingyangmycin can be used as the therapy of choice for capillary, mixed and cavernous hemangiomas in oral and maxillofacial region. "