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surfomer

hypolipidemic; RN & structure available in JAMA 1980;243(16):1663

Also Known As:

AOMA; poly(1,2-dicarboxy-3-hexadecyl-1,4-butanediyl); poly(1,2-dicarboxy-3-hexadecyltetramethylene)

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Macromolecular Substances: 97
- Polymers: 13051
  - surfomer: 2
Biomedical and Dental Materials
- Polymers: 13051
  - surfomer: 2
Technology, Industry, and Agriculture
- Manufactured Materials
  - Biomedical and Dental Materials
    - Polymers: 13051
      - surfomer: 2
Organic Chemicals: 133
- Carboxylic Acids: 973
  - Acyclic Acids
    - Dicarboxylic Acids: 108
      - Succinates: 13
        surfomer: 2

Related Diseases

1.	Hypothyroidism 04/01/1987 - "Maneuvers that augmented intestinal cholesterol uptake (particularly hypothyroidism) appeared to suppress intestinal apoB-48 synthesis by over 40%, while Surfomer (AOMA) administration reduced cholesterol absorption (control, 54 +/- 7%; AOMA, 26 +/- 8%; P less than 0.0005) and resulted in a 24% increase in apoB-48 synthesis by jejunal enterocytes. "
2.	Hyperlipidemias (Hyperlipidemia) 07/01/1982 - "To evaluate AOMA in man, we studied its effects on plasma cholesterol, cholesterol absorption, fecal excretion of cholesterol and its bacterial degradation products, coprostanol and coprostanone, and percent saturation of gallbladder bile with cholesterol in 20 individuals chosen for hyperlipidemia. "

Related Drugs and Biologics

1.	Cholesterol
2.	surfomer
3.	Apolipoprotein B-48
4.	Cholestanol (Coprostanol)
5.	coprostanone