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manganese chloride (manganese chloride, tetrahydrate)

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RN given refers to parent cpd with MF of MnCl2

Also Known As:

manganese chloride, tetrahydrate; manganese dichloride; MnCl2; manganese chloride, 52Mn-labeled; manganese chloride, diammoniate; manganese chloride, dihydrate; manganese chloride, hexaammoniate; manganese chloride, hexahydrate; manganese chloride, monoammoniate; manganous chloride; manganese chloride (MnCl2)

Networked: 113 relevant articles (5 outcomes, 6 trials/studies)

Relationship Network

Drug Context: Research Results

Inorganic Chemicals: 9

Experts

1.	Johansson, Lars: 3 articles (04/2014 - 05/2004)
2.	Shukakidze, A A: 3 articles (01/2009 - 01/2001)
3.	Bikashvili, T Z: 3 articles (01/2009 - 01/2001)
4.	Wang, Yi: 2 articles (08/2015 - 01/2015)
5.	Yeger, Herman: 2 articles (03/2015 - 01/2014)
6.	Alhamami, Mosa: 2 articles (03/2015 - 01/2014)
7.	Ganesh, Tameshwar: 2 articles (03/2015 - 01/2014)
8.	Yang, Bo-ning: 2 articles (06/2013 - 03/2010)
9.	Aoki, Ichio: 2 articles (05/2011 - 02/2006)
10.	Fu, Juanling: 2 articles (08/2008 - 10/2003)

Related Diseases

1.	Neoplasms (Cancer) 03/01/2015 - "MnCl2 -induced R1 changes compared with Gd-induced changes were significantly greater in both ZR75 (P < 0.01) and LM2 tumors (P < 0.05). " 03/01/2015 - "MnCl2 administration achieved greater and more uniform enhancement throughout the tumor mass (i.e., not restricted to the tumor periphery), with R1 changing over 20% in 72% of tumors. " 01/01/2012 - "To the best of our knowledge, this is the first study reporting direct in-vitro MnCl2 labelling and 7 T based in-vivo MRI tracing of cancer cells in a model of prostate cancer. " 05/01/1990 - "T1 weighted, magnetic resonance images obtained at 0.5 T of an R3230 adenocarcinoma implanted in the liver showed an increase in the signal intensity of both normal liver and tumor tissue after the injection of free MnCl2 (25 mumole/kg). " 01/01/1984 - "The growth of B16-F10 melanoma lung tumors was inhibited in mice injected with MnCl2 one day before tumor challenge. "
2.	Ischemia 07/01/2005 - "In conclusion, the intracellular contrast agent MnCl2 enhances the canine heart and shows promise in detecting ischemia at doses that do not cause adverse cardiac effects." 04/01/1998 - "The aim of the present work was to provide a reference study of the effects of manganese itself (MnCl2) on isolated rat hearts submitted to global total normothermic ischemia (30 min) and reperfusion (60 min). " 05/01/1995 - "Effects of dimethyl sulfoxide, allopurinol, 21-aminosteroid U-74389G, and manganese chloride on low-flow ischemia and reperfusion of the large colon in horses."
3.	Anoxia (Hypoxia) 03/01/1981 - "2. MnCl2 (5 mM), after 60 min of hypoxia, abolished overshoot increased resting potential, and further reduced action potential duration. " 01/01/1995 - "The intrarenal infusion of manganese chloride, another calcium channel blocker, was also effective in blunting the hypoxemia-induced changes in the left infused kidney, but not in the contralateral kidney. " 04/01/1989 - "Effects of manganese chloride, verapamil, and hypoxia on the rate-dependent increase in internal longitudinal resistance of rabbit myocardium." 09/01/1998 - "Hypoxia reduced the production of cAMP induced by isoproterenol (36% decrease in the RV and 41% decrease in the LV), 5'-guanylylimododiphosphate (40% decrease in the RV and 42% decrease in the LV), and forskolin (39% decrease in the RV and 41% decrease in the LV) but did not alter the effect of MnCl2 and NaF. "
4.	Neoplasm Metastasis (Metastasis) 05/01/1990 - "These results suggest that liposome encapsulated MnCl2 has excellent potential as a liver specific contrast agent for the improved detection of liver metastases."
5.	Hemolysis 03/15/1984 - "Addition of catalase, MnCl2, CoCl2 or dithiothreitol in vitro showed significant protection against the hemolysis induced by Tween 20 in vitamin E-deficient chick and kid erythrocytes."

Related Drugs and Biologics

1.	Catalase
2.	Calcium Channels (Calcium Channel)
3.	Vitamin E
4.	Polysorbates (PSML)
5.	Liposomes (Liposome)
6.	Dithiothreitol (Cleland's Reagent)
7.	Manganese
8.	Insulin (Novolin)
9.	Transcription Factors (Transcription Factor)
10.	Heparin (Liquaemin)

Related Therapies and Procedures

1.	Intraperitoneal Injections
2.	Injections
3.	Intravenous Infusions
4.	Intravenous Injections
5.	Aftercare (After-Treatment)