polyphenols

GEN only; use the precise structure header, most commonly in the FLAVONOIDS group; this term only refers vaguely to phenolic (aromatic) hydroxyls; provinols are polyphenols from red wine

Also Known As:

Networked: 1847 relevant articles (151 outcomes, 389 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Mukhtar, Hasan: 21 articles (01/2015 - 01/2003)
2.	Yang, Chung S: 19 articles (06/2013 - 09/2002)
3.	Dou, Q Ping: 15 articles (10/2012 - 10/2002)
4.	Andriantsitohaina, Ramaroson: 14 articles (11/2012 - 03/2002)
5.	Schini-Kerth, Valérie B: 13 articles (12/2015 - 09/2006)
6.	Lambert, Joshua D: 13 articles (06/2011 - 02/2003)
7.	Scalbert, Augustin: 12 articles (11/2015 - 10/2003)
8.	Segura-Carretero, Antonio: 12 articles (09/2015 - 01/2007)
9.	Heber, David: 12 articles (04/2015 - 05/2004)
10.	Auger, Cyril: 11 articles (12/2015 - 03/2004)

Related Diseases

1.	Neoplasms (Cancer) 01/01/2001 - "Epidemiological studies concerning polyphenol consumption and human cancer risk suggest the protective effects of certain food items and polyphenols, but more studies are needed for clear-cut conclusions. " 10/01/2008 - "Total polyphenols isolated from the wine were more effective in reducing tumor growth as compared with a hydrophobic polyphenol fraction isolated from the wine, showing a 50% and 60% reduction in tumor growth on day 33, respectively. " 11/01/2013 - "Therefore, the main objective of the present study was the assessment in stem extracts from Greek Vitis vinifera varieties of the total polyphenolic content (TPC), the identification of the polyphenols present in them, and the evaluation of their antioxidant activity, protection against ROS-induced DNA damage and inhibition of liver (HepG2) and cervical (HeLa) cancer cell growth. " 07/01/2012 - "This review summarizes the main protective effects on the cardiovascular system and cancer resulting from moderate wine and beer intake due mainly to their common components, alcohol and polyphenols." 10/01/2010 - "The therapeutic efficacy of these polyphenols on tumor growth and the SphK1/S1P pathway were confirmed in animals using a heterotopic PC-3 tumor in place model. "
2.	Cardiovascular Diseases (Cardiovascular Disease) 11/01/2008 - "The aim of this review is to discuss the accumulating evidence that suggests that grape extracts and purified grape polyphenols possess a diverse array of biological actions and may be beneficial in the prevention of some inflammatory-mediated diseases including cardiovascular disease. " 06/08/2011 - "This study provides the possibility that polyphenols in passion fruit seeds are effective against cardiovascular diseases (CVDs)." 01/01/2007 - "Wine polyphenols are considered to be protective against cardiovascular diseases. " 12/01/2011 - "Grapes and related products, such as juices, and in particular, their polyphenols, have previously been associated with many health benefits, such as protection against cardiovascular disease. " 05/01/2013 - "Effects of wine, alcohol and polyphenols on cardiovascular disease risk factors: evidences from human studies."
3.	Inflammation 09/01/2010 - "Therefore, activation of SIRT1 by polyphenols is beneficial for regulation of calorie restriction, oxidative stress, inflammation, cellular senescence, autophagy/apoptosis, autoimmunity, metabolism, adipogenesis, circadian rhythm, skeletal muscle function, mitochondria biogenesis and endothelial dysfunction. " 11/01/2007 - "Understanding the regulatory steps and the multiple potential actions of polyphenols within the inflammatory cascade may help to define special polyphenols to be used for prevention and intervention in clinical conditions of inflammation. " 12/01/2009 - "In conclusion, the administration of Marie Ménard apples, rich in polyphenols and used at present only in the manufacturing of cider, ameliorates colon inflammation in transgenic rats developing spontaneous intestinal inflammation, suggesting the possible use of these and other apple varieties to control inflammation in IBD patients." 03/12/2014 - "This study assessed the effects of polyphenols on intestinal inflammation, using the physiologically relevant Caco-2 Transwell model and using lipopolysaccharide (LPS) to trigger inflammation. " 01/01/2014 - "In this study, we developed a stable and effective strategy to administer polyphenols to treat in vivo models of acute intestinal inflammation. "
4.	Chronic Disease (Chronic Diseases) 01/01/2014 - "Polyphenols are effective against chronic diseases and recent reports indicated strong epigenetic effects of polyphenols. " 06/01/2008 - "Polyphenols are widely distributed in plant foods, and have been linked to improved human health through reduced risk of chronic diseases, especially cardiovascular. " 09/01/2013 - "Epidemiological, clinical, and animal studies support a role of polyphenols in the prevention of various chronic diseases. " 12/01/2015 - "We summarize the recent findings concerning the effects of polyphenols on human chronic disease and the future directions for research to increase the amount of these compounds in wine. " 09/01/2015 - "Extracts 3 and 7 (undergoing the combinations of clarification and centrifugation, and astringency removal, centrifugation and pasteurization, respectively) contained more polyphenols, which may help reduce risk of chronic diseases. "
5.	Prostatic Neoplasms (Prostate Cancer) 01/01/2015 - "Although results are sometimes inconsistent and variable, there is a general agreement that polyphenols hold great promise for the future management of prostate cancer. " 01/01/2012 - "Different compounds are available and certainly polyphenols represent those with efficacy against prostate cancer. " 01/01/2014 - "Fruit and vegetables and polyphenols may be preventive in prostate cancer, but further studies are needed to draw more solid conclusions and to clarify their role in patients with an established diagnosis of prostate cancer. " 01/01/2015 - "This article provides a systematic review of the health benefits of selected dietary polyphenols in prostate cancer, especially focusing on the subclasses of polyphenols, which have a great effect on disease prevention and treatment. " 01/01/2015 - "The relationship between dietary polyphenols and the prevention of prostate cancer has been examined previously. "

Related Drugs and Biologics

1.	Tea
2.	Flavonoids
3.	Antioxidants
4.	Anthocyanins (Anthocyanin)
5.	Carotenoids (Carotene)
6.	resveratrol
7.	Ascorbic Acid (Vitamin C)
8.	Insulin (Novolin)
9.	Vitamin E
10.	Ethanol (Ethyl Alcohol)

Related Therapies and Procedures

1.	Chemoprevention
2.	Drug Therapy (Chemotherapy)
3.	Therapeutics
4.	Intraperitoneal Injections
5.	Intra-Articular Injections