early pregnancy factor

immunosuppressive factor detected in serum of animals, also a chaperonin protein found in the mitochondria

Also Known As:

Cpn10 protein, human; HSPE1 protein, human; Hspe1 protein, mouse; Hspe1 protein, rat; embryo-associated immunosuppressive factor; heat shock 10kDa protein 1 (chaperonin 10), human; heat shock protein 1 (chaperonin 10), mouse; heat shock protein 1 (chaperonin 10), rat; serum EASF; serum immunosuppressive factor

Networked: 27 relevant articles (0 outcomes, 6 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Morton, Halle: 3 articles (12/2003 - 08/2003)
2.	Cavanagh, Alice C: 2 articles (10/2003 - 08/2003)
3.	Hillyard, Narelle C: 2 articles (10/2003 - 08/2003)
4.	McCombe, Pamela A: 2 articles (10/2003 - 08/2003)
5.	Zhang, Bing: 2 articles (10/2003 - 08/2003)
6.	Anzalone, Rita: 1 article (01/2010)
7.	Campanella, Claudia: 1 article (01/2010)
8.	Cappello, Francesco: 1 article (01/2010)
9.	Conway de Macario, Everly: 1 article (01/2010)
10.	Corrao, Simona: 1 article (01/2010)

Related Diseases

1.	Trophoblastic Neoplasms (Trophoblastic Tumor) 03/01/1999 - "A study of early pregnancy factor activity in the sera of women with trophoblastic tumor." 07/01/1987 - "Detection of early pregnancy factor-like activity in women with gestational trophoblastic tumors." 03/01/1999 - "To detect whether or not the early pregnancy factor (EPF)-like activity, or chaperonin 10, could be in the sera of patients with trophoblastic tumor in order to find another more efficient means to diagnose this kind of tumor. "
2.	Habitual Abortion (Recurrent Miscarriage) 08/01/1991 - "The early pregnancy factor (EPF) in pregnancies of women with habitual abortions." 04/01/1994 - "In a study it was investigated to what extent the early pregnancy factor, the placental proteins 12 and 14 and tumor necrosis factor alpha are suited to control and select patients with habitual abortions for immunotherapy. " 04/01/1994 - "[Passive immunotherapy with Venimmun for the prevention of habitual abortion--early pregnancy factor, placenta protein 12, placenta protein 14, tumor necrosis factor alpha--parameters for monitoring immunotherapy]."
3.	Tubal Pregnancy 05/01/1988 - "In the present study, the diagnostic value of the Early Pregnancy Factor (EPF), progesterone, and endosonography was investigated in 142 patients with suspected tubal pregnancy. " 05/01/1988 - "[Tubal pregnancies: early pregnancy factor, progesterone, beta-HCG and vaginal sonography as differential diagnostic parameters]."
4.	Ovarian Neoplasms (Ovarian Cancer) 06/01/2006 - "Studies in pregnancy have demonstrated similar T-cell dysfunction mediated, at least in part, by HSP10, identified as "early pregnancy factor." This pilot study addresses the presence of HSP10 in the circulation of ovarian cancer patients and assesses its role in suppressing CD3-zeta. "
5.	Multiple Myeloma 09/01/1984 - "[Studies on a serum immunosuppressive factor in multiple myeloma]."

Related Drugs and Biologics

1.	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)
2.	Progesterone
3.	Pregnancy Proteins
4.	Proteins (Proteins, Gene)
5.	Myelin Basic Protein
6.	Intercellular Signaling Peptides and Proteins (Growth Factors)
7.	Myelin Proteolipid Protein
8.	Chaperonin 10
9.	Complementary DNA (cDNA)
10.	Cytokines

Related Therapies and Procedures

1.	Immunotherapy
2.	Induced Abortion (Induced Abortions)