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KWD 2131
beta-agonist; RN refers to sulfate salt (2:1); structure given in first source
Also Known As:
1,3-benzenediol, 5-(1-hydroxy-2-((2-hydroxy-1,1-dimethylethyl)amino)ethyl)-, sulfate (2:1) (salt); 1-(3,5-dihydroxyphenyl)-2-((1,1-dimethyl-2-hydroxyethyl)amino)ethanol sulfate; KWD 2131 monosulfate; KWD 2131sulfate; KWD-2131
Networked:
8
relevant articles (
0
outcomes,
3
trials/studies)
Bio-Agent Context: Research Results
Organic Chemicals: 133
Amines: 4871
Amino Alcohols: 20
Ethanolamines: 16
Terbutaline: 1130
KWD 2131: 8
Alcohols: 595
Amino Alcohols: 20
Ethanolamines: 16
Terbutaline: 1130
KWD 2131: 8
Related Diseases
1.
Seasonal Allergic Rhinitis (Hay Fever)
09/01/1982 - "
Topical treatment of seasonal allergic rhinitis with a beta-adrenoceptor stimulant (KWD 2131).
"
09/01/1982 - "
During 4 weeks of the grass pollen season in the south of Sweden 27 patients with seasonal allergic rhinitis were treated topically with a beta-adrenoceptor stimulant, KWD 2131, which in an earlier rhinomanometric study had shown a prophylactic effect at nasal allergen provocations in hay-fever patients.
"
01/01/1980 - "
The effects of the beta-adrenoceptor stimulating drugs, terbutaline (Bricanyl) and KWD 2131, on the increase in nasal airway resistance induced by pollen extracts, have been studied in a placebo-controlled double-blind crossover trial of 13 asymptomatic (out of season) patients with hay fever.
"
2.
Hypersensitivity (Allergy)
10/01/1981 - "
During the 2 days' study, 10 patients with known type I-allergy in the skin were randomly assigned to the KWD 2131 or terbutaline group.
"
3.
Asthma (Bronchial Asthma)
03/01/1980 - "
Pretreatment with KWD 2131, before histamine challenge, showed that the subthreshold dose for bronchodilatation was 0.5 mg in nine patients and 0.25 mg in three patients compared with 1 mg in patients with intrinsic asthma.
"
07/01/1980 - "
The selective anti-allergic effect of a new beta-agonist, KWD 2131, in inhibiting allergen-provoked asthma was compared with that of placebo in a double-blind crossover study.
"
03/01/1980 - "
The equipotent bronchodilating doses of terbutaline and a new beta-agonist KWD 2131 with a relatively stronger anti-allergic (inhibition of mediator release) than bronchodilating effect given in nebulized form was estimated in eight patients with intrinsic asthma.
"
4.
Bronchial Spasm
07/01/1980 - "
Evaluation of the protective effect of a new beta-agonist, KWD 2131, on allergen-induced bronchospasm.
"
08/01/1982 - "
The protective property of equipotent bronchodilating doses of inhaled KWD 2131 and terbutaline against allergen-induced bronchospasm.
"
08/01/1982 - "
The anti-allergic capacity of nebulized KWD 2131 in inhibiting allergen-induced bronchospasm was compared with that of terbutaline in equipotent bronchodilating doses.
"
5.
Allergic Rhinitis
09/01/1980 - "
The effects of nasal airway resistance of the beta-adrenoceptor stimulants terbutaline (Bricanyl) and KWD 2131 intranasally have been studied by means of posterior rhinomanometry in 16 healthy volunteers and 13 asymptomatic patients with allergic rhinitis.
"
Related Drugs and Biologics
1.
Terbutaline (Brethaire)
2.
Adrenergic Receptors (Adrenergic Receptor)
3.
Allergens
4.
Anti-Allergic Agents (Antiallergic Agents)
5.
Histamine (Histamine Dihydrochloride)