KWD 2131

beta-agonist; RN refers to sulfate salt (2:1); structure given in first source

Also Known As:

1,3-benzenediol, 5-(1-hydroxy-2-((2-hydroxy-1,1-dimethylethyl)amino)ethyl)-, sulfate (2:1) (salt); 1-(3,5-dihydroxyphenyl)-2-((1,1-dimethyl-2-hydroxyethyl)amino)ethanol sulfate; KWD 2131 monosulfate; KWD 2131sulfate; KWD-2131

Networked: 8 relevant articles (0 outcomes, 3 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Amines: 4871
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Terbutaline: 1130
        KWD 2131: 8
- Alcohols: 595
  - Amino Alcohols: 20
    - Ethanolamines: 16
      - Terbutaline: 1130
        KWD 2131: 8

Related Diseases

1.	Seasonal Allergic Rhinitis (Hay Fever) 09/01/1982 - "Topical treatment of seasonal allergic rhinitis with a beta-adrenoceptor stimulant (KWD 2131)." 09/01/1982 - "During 4 weeks of the grass pollen season in the south of Sweden 27 patients with seasonal allergic rhinitis were treated topically with a beta-adrenoceptor stimulant, KWD 2131, which in an earlier rhinomanometric study had shown a prophylactic effect at nasal allergen provocations in hay-fever patients. " 01/01/1980 - "The effects of the beta-adrenoceptor stimulating drugs, terbutaline (Bricanyl) and KWD 2131, on the increase in nasal airway resistance induced by pollen extracts, have been studied in a placebo-controlled double-blind crossover trial of 13 asymptomatic (out of season) patients with hay fever. "
2.	Hypersensitivity (Allergy) 10/01/1981 - "During the 2 days' study, 10 patients with known type I-allergy in the skin were randomly assigned to the KWD 2131 or terbutaline group. "
3.	Asthma (Bronchial Asthma) 03/01/1980 - "Pretreatment with KWD 2131, before histamine challenge, showed that the subthreshold dose for bronchodilatation was 0.5 mg in nine patients and 0.25 mg in three patients compared with 1 mg in patients with intrinsic asthma. " 07/01/1980 - "The selective anti-allergic effect of a new beta-agonist, KWD 2131, in inhibiting allergen-provoked asthma was compared with that of placebo in a double-blind crossover study. " 03/01/1980 - "The equipotent bronchodilating doses of terbutaline and a new beta-agonist KWD 2131 with a relatively stronger anti-allergic (inhibition of mediator release) than bronchodilating effect given in nebulized form was estimated in eight patients with intrinsic asthma. "
4.	Bronchial Spasm 07/01/1980 - "Evaluation of the protective effect of a new beta-agonist, KWD 2131, on allergen-induced bronchospasm." 08/01/1982 - "The protective property of equipotent bronchodilating doses of inhaled KWD 2131 and terbutaline against allergen-induced bronchospasm." 08/01/1982 - "The anti-allergic capacity of nebulized KWD 2131 in inhibiting allergen-induced bronchospasm was compared with that of terbutaline in equipotent bronchodilating doses. "
5.	Allergic Rhinitis 09/01/1980 - "The effects of nasal airway resistance of the beta-adrenoceptor stimulants terbutaline (Bricanyl) and KWD 2131 intranasally have been studied by means of posterior rhinomanometry in 16 healthy volunteers and 13 asymptomatic patients with allergic rhinitis. "

Related Drugs and Biologics

1.	Terbutaline (Brethaire)
2.	Adrenergic Receptors (Adrenergic Receptor)
3.	Allergens
4.	Anti-Allergic Agents (Antiallergic Agents)
5.	Histamine (Histamine Dihydrochloride)