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S-nitroso-N-acetylcysteine

activates bovine coronary arterial & rat hepatic soluble guanylate cyclase; RN given refers to (L)-isomer

Also Known As:

S-nitrosoacetylcysteine; L-cysteine, N-acetyl-S-nitroso-

Networked: 14 relevant articles (2 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Sulfur Compounds: 278
  - Sulfur Amino Acids: 221
    - Cysteine: 6760
      - Acetylcysteine: 4440
        S-nitroso-N-acetylcysteine: 14
Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675
  - Sulfur Amino Acids: 221
    - Cysteine: 6760
      - Acetylcysteine: 4440
        S-nitroso-N-acetylcysteine: 14

Experts

1.	de Oliveira, Marcelo G: 4 articles (01/2013 - 03/2006)
2.	de Oliveira, Marcelo Ganzarolli: 3 articles (01/2016 - 11/2006)
3.	Carrilho, Flair J: 3 articles (01/2013 - 03/2006)
4.	de Oliveira, Claudia P M S: 3 articles (01/2013 - 03/2006)
5.	de Souza, Gabriela Freitas Pereira: 2 articles (01/2016 - 01/2012)
6.	Laurindo, Francisco Rafael Martins: 2 articles (01/2014 - 11/2006)
7.	de Souza, Gabriela F P: 2 articles (01/2013 - 04/2010)
8.	Laurindo, Francisco R M: 2 articles (04/2008 - 03/2006)
9.	Simplicio, Fernanda I: 2 articles (04/2008 - 03/2006)
10.	Bruni-Cardoso, Alexandre: 1 article (01/2014)

Related Diseases

1.	Fibrosis (Cirrhosis) 04/01/2010 - "This study was aimed to investigate the molecular mechanisms underlying prevention of hepatic fibrosis by S-nitroso-N-acetylcysteine (SNAC), a nitric oxide donor that inhibits lipid peroxidation. " 01/01/2016 - "The primary S-nitrosothiol, S-nitroso-N-acetylcysteine (SNAC) is a nitric oxide donor with potential pharmaceutical applications for the oral treatment of hepatic steatosis and cirrhosis and for protection against gastric acid-peptic disorders. "
2.	Reperfusion Injury 07/01/2010 - "S-nitroso-N-acetylcysteine ameliorates ischemia-reperfusion injury in the steatotic liver." 12/01/2010 - "S-nitroso-N-acetylcysteine: a promising drug for early ischemia/reperfusion injury in rat liver." 01/01/1998 - "S-nitroso-N-acetylcysteine protects skeletal muscle against reperfusion injury."
3.	Atherosclerotic Plaque (Atheroma) 01/30/2014 - "Previous studies from our group have demonstrated the protective effect of S-nitroso-N-acetylcysteine (SNAC) on the cardiovascular system in dyslipidemic LDLr-/- mice that develop atheroma and left ventricular hypertrophy after 15 days on a high fat diet. "
4.	Left Ventricular Hypertrophy (Ventricular Hypertrophy, Left) 01/30/2014 - "Previous studies from our group have demonstrated the protective effect of S-nitroso-N-acetylcysteine (SNAC) on the cardiovascular system in dyslipidemic LDLr-/- mice that develop atheroma and left ventricular hypertrophy after 15 days on a high fat diet. "
5.	Keratitis 01/01/2012 - "The purpose of this study was to evaluate the antimicrobial activity of two nitric oxide donors, ie, S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylcysteine (SNAC), against clinical isolates from patients with infectious keratitis. "

Related Drugs and Biologics

1.	Nitric Oxide Donors
2.	S-Nitrosothiols
3.	S-Nitrosoglutathione
4.	Hydrogels
5.	Nitrites
6.	Phosphates (Orthophosphate)
7.	Methionine (L-Methionine)
8.	Choline (Choline Chloride)

Related Therapies and Procedures

1.	Oral Administration