symmetric dimethylarginine

Also Known As:

N(G1),N(G2)-dimethylarginine; N,N'-dimethylarginine; NG,N'G-dimethyl-L-arginine; guanidino-N(1),N(2)-dimethylarginine; omega-N(G),N'(G)-dimethylarginine; sDMA arginine; L-ornithine, N(5)-((methylamino)(methylimino)methyl)-

Networked: 244 relevant articles (2 outcomes, 35 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Amino Acids: 30675

Experts

1.	Schwedhelm, Edzard: 14 articles (10/2021 - 02/2010)
2.	Böger, Rainer H: 11 articles (07/2020 - 02/2010)
3.	Bode-Böger, Stefanie M: 8 articles (12/2019 - 11/2012)
4.	Martens-Lobenhoffer, Jens: 8 articles (12/2019 - 01/2011)
5.	Nagy, Lajos: 7 articles (01/2022 - 01/2016)
6.	Weissenborn, Karin: 7 articles (12/2019 - 01/2011)
7.	Worthmann, Hans: 7 articles (12/2019 - 01/2011)
8.	Kielstein, Jan T: 6 articles (01/2020 - 11/2012)
9.	Molnar, Tihamer: 5 articles (01/2022 - 01/2016)
10.	Lichtinghagen, Ralf: 5 articles (12/2019 - 11/2012)

Related Diseases

1.	Acute Kidney Injury (Acute Renal Failure) 02/01/2022 - "So, the present study aimed to evaluate symmetric dimethylarginine (SDMA) and Doppler ultrasonography including resistive index (RI) in the diagnosis of acute kidney injury in dogs. " 01/15/2021 - "Detecting acute kidney injury in horses by measuring the concentration of symmetric dimethylarginine in serum." 10/20/2020 - "Serum symmetric dimethylarginine concentration in healthy horses and horses with acute kidney injury." 09/01/2022 - "Evaluation of symmetric dimethylarginine in cats with acute kidney injury and chronic kidney disease." 05/01/2017 - "Plasma Symmetric Dimethylarginine Concentration in Dogs with Acute Kidney Injury and Chronic Kidney Disease."
2.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 02/01/2010 - "Symmetric dimethylarginine, an endogenous marker of glomerular filtration rate, and the risk for microalbuminuria in young people with type 1 diabetes." 02/01/2010 - "To perform a cross-sectional comparison of endogenous markers of glomerular filtration rate (GFR) (plasma symmetric dimethylarginine (SDMA) and estimated GFR (eGFR)) with a direct measure of GFR (using the plasma clearance of Inutest (In-GFR)), and a longitudinal evaluation of these markers in relation to the development of microalbuminuria, in young people with type 1 diabetes (T1D). " 08/01/2009 - "To investigate the roles of insulin, glucose, and oxidative stress on plasma asymmetric and symmetric dimethylarginine (ADMA, SDMA) levels in complicated diabetes, we studied patients with type 1 diabetes (T1D; n = 20), T1D + end-stage renal disease under hemodialysis (T1D + ESRD; n = 12), T1D + ESRD who received kidney transplant (KD; n = 16), and T1D + ESRD who received kidney-pancreas transplant (KP; n = 20) and healthy controls (n = 50). "
3.	Chronic Renal Insufficiency 01/01/2023 - "Symmetric dimethylarginine (SDMA) is an independent cardiovascular risk factor in patients with chronic kidney diseases, which is mostly excreted through renal tubules. " 01/01/2022 - "Blood concentration of symmetric dimethylarginine correlates with kidney damage as assessed with a proposed histologic grading system for chronic kidney disease in tigers (Panthera tigris)." 01/01/2021 - "This article will review current research on symmetric dimethylarginine and the ways in which it may be utilised in small animal practice; current research supports the use of symmetric dimethylarginine as a screening test for detection of early chronic kidney disease according to International Renal Interest Society guidelines, but further research is required in to the usefulness of symmetric dimethylarginine as a tool for monitoring disease and the effect of non-renal influences." 08/19/2020 - "Renal ultrasonographic strain elastography and symmetric dimethylarginine (SDMA) in canine and feline chronic kidney disease." 01/01/2020 - "Thus, our data suggest that symmetric dimethylarginine in d-HDL mediates glycocalyx breakdown in chronic kidney disease."
4.	Hyperthyroidism 01/01/2023 - "Changes in symmetric dimethylarginine and glomerular filtration rates in hyperthyroid cats undergoing radioiodine therapy." 09/01/2022 - "Finally, this review explores the use of symmetric dimethylarginine (SDMA) in assessing renal function before and after treatment in hyperthyroid cats. " 01/01/2018 - "To investigate serum symmetric dimethylarginine (SDMA) concentration as a potential marker of masked azotemia in untreated hyperthyroid cats. " 01/01/2018 - "Evaluation of Serum Symmetric Dimethylarginine Concentration as a Marker for Masked Chronic Kidney Disease in Cats With Hyperthyroidism." 01/01/2023 - "The aims of this study were to evaluate concentrations of symmetric dimethylarginine (SDMA) in hyperthyroid cats before and after radioiodine treatment, and to compare results with other variables used to assess kidney function in cats (creatinine, urine specific gravity [USG] and glomerular filtration rate [GFR] measured by renal scintigraphy). "
5.	Neoplasms (Cancer) 11/02/2023 - "GSK595 decreased the global symmetric dimethylarginine level, the proliferation rate and clonogenicity of STS cell lines in vitro and tumor growth in vivo. " 12/01/2022 - "The association between symmetric dimethylarginine concentrations and various neoplasms in dogs and cats." 01/01/2017 - "The three tissue specimens were taken by surgery (tumor, adjacent and healthy tissue) and the concentrations of NO2+NO3, asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) were determined in the tissue specimens. " 10/01/2022 - "Daily oral administration of MRTX1719 to tumor xenograft-bearing mice demonstrated dose-dependent inhibition of PRMT5-dependent symmetric dimethylarginine protein modification in MTAP-deleted tumors that correlated with antitumor activity. " 01/01/2023 - "The aim of this study was to assess the concentrations of ADMA, symmetric dimethylarginine (SDMA) and L-arginine in rats exposed to N-nitroso-N-methylurea (NMU) for the induction of mammary tumors. "

Related Drugs and Biologics

1.	Creatinine
2.	Biomarkers (Surrogate Marker)
3.	Tryptophan (L-Tryptophan)
4.	sinistrin
5.	N,N-dimethylarginine (asymmetric dimethylarginine)
6.	Arginine (L-Arginine)
7.	dimethylarginine
8.	Citrulline
9.	Homoarginine
10.	Brain Natriuretic Peptide (Natrecor)

Related Therapies and Procedures

1.	Therapeutics
2.	Aftercare (After-Treatment)
3.	Decompression
4.	Renal Dialysis (Hemodialysis)
5.	Percutaneous Coronary Intervention