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dihydrocytochalasin B

inhibits cell motility in many eucaryotic cells

Also Known As:

dihydrocytochalasin C; dihydrocytochalasin D

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Cytochalasins: 40
        Cytochalasin B: 450
        dihydrocytochalasin B: 4
Biological Factors: 2472
- Biological Toxins: 20
  - Mycotoxins: 1745
    - Cytochalasins: 40
      - Cytochalasin B: 450
        dihydrocytochalasin B: 4

Experts

1.	Chen, Yu: 1 article (07/2012)
2.	Foucar, Charles E: 1 article (07/2012)
3.	Ma, Hoi Tang: 1 article (07/2012)
4.	Man, Wing Yu: 1 article (07/2012)
5.	Marxer, Miriam: 1 article (07/2012)
6.	Poon, Randy Y C: 1 article (07/2012)
7.	Abdulkadir, Sarki A: 1 article (02/2012)
8.	Roh, Meejeon: 1 article (02/2012)
9.	van der Meer, Riet: 1 article (02/2012)

Related Diseases

1.	Tetraploidy 07/01/2012 - "In support of this, abolition of cytokinesis with dihydrocytochalasin B resulted in similar effects on tetraploid cells as Aurora B inhibition. "
2.	Wounds and Injuries (Trauma) 07/01/1981 - "Epidermal closure of skin wounds on newt limb explants was inhibited to equal degrees by cytochalasins B,D and dihydrocytochalasin B (H2CB). "
3.	Polyploidy 02/01/2012 - "ROS levels and mitochondrial mass are also higher in dihydrocytochalasin B (DCB)-induced polyploid cells, suggesting that higher levels of ROS observed in polyploid cell can occur due to cytokinesis failure. "
4.	Carcinoma (Carcinomatosis) 01/01/1995 - "The accumulation of [3H]-vinblastine by MCF-7/ADR cells and by drug-resistant human ovarian carcinoma cells (SKVLB1) was increased to the greatest extent by verapamil, followed by dihydrocytochalasin B > cytochalasin E > cytochalasin B, whereas cytochalasins A, C, D, H, and J did not alter intracellular accumulation of the drug. "
5.	Breast Neoplasms (Breast Cancer) 01/01/1995 - "Dihydrocytochalasin B and cytochalasin E consistently sensitized P-glycoprotein-overexpressing human breast carcinoma cells (MCF-7/ADR) to daunomycin, vinblastine, and actinomycin D without affecting the cytotoxicity of cisplatin. "

Related Drugs and Biologics

1.	Cytochalasins
2.	Member 1 Subfamily B ATP Binding Cassette Transporter
3.	Vinblastine (Vinblastine Sulfate)
4.	Verapamil (Calan)
5.	Daunorubicin (Cerubidine)
6.	Dactinomycin (Actinomycin)
7.	Cytochalasin B
8.	Cisplatin (Platino)
9.	cytochalasin E