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5-methylnicotinamide

potentiates cytotoxicity of N-methyl-N-nitrosourea

Also Known As:

5-methyl-3-pyridinecarboxamide

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyridines: 88
    - Nicotinic Acids: 13
      - Niacinamide: 2223
        5-methylnicotinamide: 2
- Heterocyclic Acids
  - Nicotinic Acids: 13
    - Niacinamide: 2223
      - 5-methylnicotinamide: 2

Related Diseases

1.	Ehrlich Tumor Carcinoma 01/01/1990 - "Exposure of Ehrlich ascites tumor cells to 3-aminobenzamide for 60 min resulted in a dose-dependent increase of cellular NAD and ATP levels at a concentration range of 0.3-5 mM. In the cells exposed to 5-methylnicotinamide there was a decrease of both nucleotide levels. "
2.	Hyperthermia 11/01/1983 - "Two inhibitors of poly(ADP-ribose) synthetase, 5-methylnicotinamide and m-methoxybenzamide, enhanced the cytotoxicity of 42 degrees C and 45 degrees C hyperthermia in cultured Chinese hamster V79 cells. "

Related Drugs and Biologics

1.	Poly Adenosine Diphosphate Ribose
2.	Nucleotides
3.	NAD (NADH)
4.	Ligases (Synthetase)
5.	Adenosine Triphosphate (ATP)
6.	3-aminobenzamide
7.	3-methoxybenzamide