resiniferatoxin

09/01/2000 - "No statistically significant improvement in mean pain score was observed in placebo group 2. During resiniferatoxin infusion 4 group 1 patients noticed a light warm or burning sensation at the suprapubic and/or urethral level. "
08/01/1997 - "In particular, resiniferatoxin is only similar in potency for induction of pain but is much more effective for desensitization. "
09/01/2000 - "We performed a randomized placebo controlled study with followup after 1 and 3 months using intravesical resiniferatoxin to treat hypersensitive disorder and bladder pain. "
09/01/2011 - "Resiniferatoxin (RTX) is a potent agonist of TRPV1, which possesses unique properties that can be utilized to treat certain modalities of pain. "
01/01/2011 - "The vanilloid agonist resiniferatoxin for interventional-based pain control."

07/13/2010 - "[Clinical study of resiniferatoxin on neurogenic bladder]."
11/01/2015 - "Resiniferatoxin (RTX) is used as an experimental drug in therapy of neurogenic urinary bladder disorders. "
07/13/2010 - "To understand the effect of resiniferatoxin on neurogenic bladder by intravesical filling. "
12/01/2001 - "Intravesical instillation of resiniferatoxin for neurogenic bladder dysfunction in a patient with myelodysplasia."
01/01/2003 - "The effect of intravesical capsaicin and resiniferatoxin in neurogenic bladder dysfunction."

06/01/2000 - "Desensitization of urinary bladder C-fibers with resiniferatoxin ameliorates bladder hyperreflexia and incontinence and supports a similar role for C-fibers in man. "
01/01/2003 - "Intravesical resiniferatoxin for refractory detrusor hyperreflexia: a multicenter, blinded, randomized, placebo-controlled trial."
08/30/1997 - "Suppression of bladder hyperreflexia by intravesical resiniferatoxin."
10/01/2000 - "Fourteen patients with detrusor hyperreflexia were instilled during 30 min, without any form of local anesthesia, with 100 ml (or the bladder capacity if lower than that volume) of 50 or 100 nM resiniferatoxin solutions in 10% alcohol in saline. "
12/01/1997 - "A total of 15 subjects with normal (8 patients) or unstable detrusor muscle (1 with detrusor instability and 6 with detrusor hyperreflexia) underwent urodynamic assessment during and after intravesical instillation of resiniferatoxin. "

05/01/2005 - "Intravesical resiniferatoxin for the treatment of interstitial cystitis: a randomized, double-blind, placebo controlled trial."
01/01/2013 - "Intravesical resiniferatoxin for the treatment of storage lower urinary tract symptoms in patients with either interstitial cystitis or detrusor overactivity: a meta-analysis."
03/01/2012 - "Effects of combination treatment of intravesical resiniferatoxin instillation and hydrodistention in patients with refractory painful bladder syndrome/interstitial cystitis: a pilot study."
11/01/2008 - "In conclusion, the effectiveness of resiniferatoxin in the treatment of interstitial cystitis remains unknown."
11/01/2008 - "Resiniferatoxin in the treatment of interstitial cystitis: a systematic review."

01/01/2012 - "In a recent study on the effects of PRF on resiniferatoxin-induced neuropathic pain in an animal model, the anti-allodynic effects of PRF were significantly greater when the PRF exposure duration was increased from 2 to 6 minutes. "
09/01/2012 - "The effect of epidural resiniferatoxin in the neuropathic pain rat model randomized trial: a complementary mechanism."
08/01/2014 - "However, NMDAR currents in spinal dorsal horn neurons are not significantly altered in rat models of diabetic neuropathic pain and resiniferatoxin-induced painful neuropathy (postherpedic neuralgia). "
07/01/2012 - "The effect of epidural resiniferatoxin in the neuropathic pain rat model."
05/01/2012 - "P2X3-mediated peripheral sensitization of neuropathic pain in resiniferatoxin-induced neuropathy."