HOME PRODUCTS COMPANY CONTACT FAQ

Research Dictionary Pharma

Sign Up FREE or Login

n-butyl nitrite (butyl nitrite)

RN given refers to parent cpd; structure in Merck Index, 9th ed, #1570

Also Known As:

butyl nitrite; n-butyl nitrite, 15N-labeled; nitrous acid, butyl ester

Networked: 13 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9
- Electrolytes: 16106
  - Ions: 7857
    - Anions: 3501
      - Nitrites: 4928
        n-butyl nitrite: 13
- Nitrogen Compounds: 67
  - Nitrous Acid: 38
    - Nitrites: 4928
      - n-butyl nitrite: 13
Organic Chemicals: 133
- Nitrites: 4928
  - n-butyl nitrite: 13

Experts

1.	Cheng, Yung-Chi: 1 article (01/2005)
2.	Dutschman, Ginger E: 1 article (01/2005)
3.	Gullen, Elizabeth A: 1 article (01/2005)
4.	Liu, Mao-Chin: 1 article (01/2005)
5.	Luo, Mei-Zhen: 1 article (01/2005)
6.	Mozdziesz, Diane E: 1 article (01/2005)
7.	Sartorelli, Alan C: 1 article (01/2005)
8.	Amitai, Yona: 1 article (01/2004)
9.	Bentur, Yedidia: 1 article (01/2004)
10.	Stalnikowicz, Ruth: 1 article (01/2004)

Related Diseases

1.	Methemoglobinemia 06/01/1985 - "The results are consistent with the hypothesis that a significant aspect of butyl nitrite toxicity is due to the resultant methemoglobinemia." 04/01/1980 - "Butyl nitrite and methemoglobinemia." 01/01/1980 - "Fatal methemoglobinemia from butyl nitrite ingestion." 09/01/1979 - "Methemoglobinemia from sniffing butyl nitrite."
2.	Kaposi Sarcoma (Kaposi's Sarcoma) 12/17/1987 - "Butyl nitrite in the induction of Kaposi's sarcoma in AIDS." 01/01/1993 - "We examined the mutagenicity of iso-butyl nitrite (IBN) vapor and aqueous IBN solution in the Ames test to help evaluate the hazard of sniffing this vapor, a habit which might play a role in the induction of Kaposi's sarcoma associated with acquired immune deficiency syndrome. "
3.	Acquired Immunodeficiency Syndrome (AIDS) 12/17/1987 - "Butyl nitrite in the induction of Kaposi's sarcoma in AIDS." 01/01/1993 - "We examined the mutagenicity of iso-butyl nitrite (IBN) vapor and aqueous IBN solution in the Ames test to help evaluate the hazard of sniffing this vapor, a habit which might play a role in the induction of Kaposi's sarcoma associated with acquired immune deficiency syndrome. "
4.	Precursor Cell Lymphoblastic Leukemia-Lymphoma (Acute Lymphoblastic Leukemia) 01/01/2005 - "Basic hydrolysis of 5, selective protection of the 2-amino and 5'-hydroxy functions with isobutyryl and silyl groups, respectively, followed by reaction with thiocarbonyldiimidazole gave the cyclic thiocarbonate, which, upon reaction with triethyl phosphite, followed by deprotection, afforded 1. Treatment of 1 with phenyl methoxyalaninylphosphochloridate and N-methylimidazole gave 2. Catalytic hydrogenation of 1 gave 3. Hydrodediazoniation of 1 with tert-butyl nitrite and tris(trimethylsilyl)silane gave 4. Compounds 1-4 were found to be inactive against the human immunodeficiency virus and exhibited minimal to no cytotoxic activity against the L1210 leukemia, CCRF-CEM lymphoblastic leukemia, and B16F10 melanoma in vitro."
5.	Neoplasms (Cancer) 08/01/1987 - "A possible explanation is that butyl nitrite, inhaled as a drug of abuse, initiates the tumor via the in vivo formation of N-nitroso compounds. "

Related Drugs and Biologics

1.	Chondroitin ABC Lyase
2.	Tetrahydrofolate Dehydrogenase (Dihydrofolate Reductase)
3.	Solutions
4.	Nitroso Compounds
5.	Keratan Sulfate
6.	Immunoglobulin G (IgG)
7.	Hydrazones
8.	Hydrazines
9.	Glycosaminoglycans
10.	Glucosephosphate Dehydrogenase (Glucose 6 Phosphate Dehydrogenase)