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6-chloromelatonin

Also Known As:

N-(2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl)acetamide

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indoles: 200
      - Tryptamines: 1679
        Melatonin: 11033
        6-chloromelatonin: 5
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Melatonin: 11033
    - 6-chloromelatonin: 5

Experts

1.	Chen, Lucy: 1 article (12/2012)
2.	Lim, Grewo: 1 article (12/2012)
3.	Mao, Jianren: 1 article (12/2012)
4.	Song, Li: 1 article (12/2012)
5.	Tan, Yonghui: 1 article (12/2012)
6.	Tian, Yinghong: 1 article (12/2012)
7.	Wang, Shuxing: 1 article (12/2012)
8.	You, Zerong: 1 article (12/2012)
9.	Hu, D N: 1 article (04/2000)
10.	Roberts, J E: 1 article (04/2000)

Related Diseases

1.	Uveal melanoma 06/01/1998 - "The melatonin derivatives also inhibited the growth of uveal melanoma cells; 6-chloromelatonin was more potent than melatonin and 6-hydroxymelatonin was the least active (6-chloromelatonin > melatonin > 6-hydroxymelatonin). " 04/01/2000 - "Uveal melanoma cells and melanocytes were cultured for 24 hr, then melatonin or one of its membrane receptor agonists, 6-chloromelatonin (Mel1a-1b) or S-20098 (Mel1b) or its putative nuclear agonist, CGP-52608 (Mel2), was added to the medium. " 02/01/1998 - "The endogenous indole melatonin and the melatonin receptor agonist 6-chloromelatonin block the proliferation of both dermal and uveal melanoma cells by mechanisms that may involve redox reactions. "
2.	Melanoma (Melanoma, Malignant) 07/15/1993 - "Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin."
3.	Hyperalgesia 12/01/2012 - "Intracisternal administration of 6-chloromelatonin (250 μg, twice daily for 7 days) concurrently attenuated mechanical hyperalgesia and depressive behavior in WKY rats as well as downregulated the NR1 expression in the ipsilateral Sp5C. "

Related Drugs and Biologics

1.	Melatonin
2.	Melatonin Receptors (Melatonin Receptor)
3.	CGP 52608
4.	agomelatine (S20098)
5.	indole
6.	6-hydroxymelatonin