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glycoursodeoxycholic acid

Also Known As:

glycine ursodeoxycholic acid; N-((3 alpha,5 beta,7 beta)-7-hydroxy-24-oxo-3-(sulfooxy) cholan-24-yl)glycine

Networked: 15 relevant articles (4 outcomes, 3 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Bile Acids and Salts: 11432
      - Cholic Acids: 14
        Deoxycholic Acid: 963
        Ursodeoxycholic Acid: 2822
        glycoursodeoxycholic acid: 15
    - Cholanes
      - Cholic Acids: 14
        Deoxycholic Acid: 963
        Ursodeoxycholic Acid: 2822
        glycoursodeoxycholic acid: 15

Experts

1.	Brites, Dora: 3 articles (07/2014 - 09/2007)
2.	Fernandes, Adelaide: 3 articles (07/2014 - 09/2007)
3.	Chen, Bo: 2 articles (01/2021 - 12/2018)
4.	Gonzalez, Frank J: 2 articles (01/2021 - 12/2018)
5.	Jiang, Changtao: 2 articles (01/2021 - 12/2018)
6.	Sun, Lulu: 2 articles (01/2021 - 12/2018)
7.	Wang, Xuemei: 2 articles (01/2021 - 12/2018)
8.	Wu, Qing: 2 articles (01/2021 - 12/2018)
9.	Wu, Yue: 2 articles (01/2021 - 12/2018)
10.	Xia, Jialin: 2 articles (01/2021 - 12/2018)

Related Diseases

1.	Necrosis 07/01/2014 - "Previous studies using monotypic nerve cell cultures have shown that bilirubin-induced neurological dysfunction (BIND) involves apoptosis and necrosis-like cell death, following neuritic atrophy and astrocyte activation,and that glycoursodeoxycholic acid (GUDCA) has therapeutic efficacy against BIND. "
2.	Atrophy 07/01/2014 - "Previous studies using monotypic nerve cell cultures have shown that bilirubin-induced neurological dysfunction (BIND) involves apoptosis and necrosis-like cell death, following neuritic atrophy and astrocyte activation,and that glycoursodeoxycholic acid (GUDCA) has therapeutic efficacy against BIND. "
3.	Atherosclerosis 01/01/2021 - "Background Although glycoursodeoxycholic acid (GUDCA) has been associated with the improvement of metabolic disorders, its effect on atherosclerosis remains elusive. " 01/01/2021 - "Glycoursodeoxycholic Acid Ameliorates Atherosclerosis and Alters Gut Microbiota in Apolipoprotein E-Deficient Mice." 01/01/2021 - "Among ApoE-/- mice fed a high-cholesterol diet (HCD), intestinal FXR deficiency (in FxrΔIE ApoE-/- mice) or direct FXR inhibition (via treatment with the FXR antagonist glycoursodeoxycholic acid [GUDCA]) decreased atherosclerosis and reduced the levels of circulating ceramides and cholesterol. "
4.	Retinal Neovascularization 06/19/2020 - "We have investigated the efficacy of the secondary bile acid ursodeoxycholic acid (UDCA) and its taurine and glycine conjugated derivatives tauroursodeoxycholic acid (TUDCA) and glycoursodeoxycholic acid (GUDCA) in preventing retinal neovascularization (RNV) in an experimental model of ROP. "
5.	Barrett Esophagus (Barrett's Esophagus) 02/01/2010 - "Protective effects of glycoursodeoxycholic acid in Barrett's esophagus cells."

Related Drugs and Biologics

1.	Bile Acids and Salts (Bile Acids)
2.	Glycine (Aminoacetic Acid)
3.	Bilirubin
4.	Ursodeoxycholic Acid (Urso)
5.	ursodoxicoltaurine
6.	Taurine
7.	Apolipoproteins
8.	Cholic Acid
9.	Lithocholic Acid
10.	Cytokines

Related Therapies and Procedures

1.	Therapeutics
2.	Oral Administration