4-guanidinobenzoate

RN given refers to parent cpd

Also Known As:

4-guanidinobenzoate, monohydrobromide; 4-guanidinobenzoate, monohydrochloride; p-guanidinobenzoic acid; para-guanidinobenzoate; 4-((aminoiminomethyl)amino)benzoic acid

Networked: 5 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133

Experts

1.	Hamagami, Kenichi: 1 article (01/2022)
2.	Hiyoshi, Hideyuki: 1 article (01/2022)
3.	Ikeda, Zenichi: 1 article (01/2022)
4.	Ishihara, Youko: 1 article (01/2022)
5.	Itono, Sachiko: 1 article (01/2022)
6.	Kakegawa, Keiko: 1 article (01/2022)
7.	Kikuchi, Fumiaki: 1 article (01/2022)
8.	Kitazaki, Tomoyuki: 1 article (01/2022)
9.	Maekawa, Tsuyoshi: 1 article (01/2022)
10.	Oki, Hideyuki: 1 article (01/2022)

Related Diseases

1.	Pancreatitis 06/01/1992 - "The study investigated the protective effect of a new synthetic protease inhibitor, E-3123, a 4-guanidinobenzoate methanesulphonate, on the exocrine pancreas in caerulein-induced pancreatitis of rats both in vivo and in vitro. " 01/01/1994 - "The effect of a novel synthetic trypsin inhibitor, 4-(2-succinimidoethylthio)-phenyl 4-guanidinobenzoate methanesulfonate (E3123), on severe acute pancreatitis was studied in trypsin-taurocholate-induced acute experimental pancreatitis in rats. "
2.	Obesity 01/01/2022 - "Design, Synthesis, and Biological Evaluation of a Novel Series of 4-Guanidinobenzoate Derivatives as Enteropeptidase Inhibitors with Low Systemic Exposure for the Treatment of Obesity."
3.	Hemolysis 01/01/1993 - "By developing 6-amidino-2-naphthyl 4-guanidinobenzoate (I, FUT-175) as a basic structure, its various derivatives were synthesized and their inhibitory activities on trypsin, plasmin, kallikrein, thrombin, C1r and C1s as well as on complement-mediated hemolysis were examined. "
4.	Dengue (Dengue Fever) 08/15/2019 - "A dibasic 4-guanidinobenzoate was previously reported as inhibitor of the dengue protease with potency in the low-micromolar range. "

Related Drugs and Biologics

1.	4-(2-succinimidoethylthio)phenyl 4-guanidinobenzoate
2.	Protease Inhibitors (Protease Inhibitor)
3.	Ceruletide
4.	Trypsin
5.	Trypsin Inhibitors
6.	Thrombin
7.	Taurocholic Acid (Sodium Taurocholate)
8.	Peptide Hydrolases (Proteases)
9.	Kallikreins (Kallikrein)
10.	Fibrinolysin