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nucleoside-diphosphatase (nucleoside diphosphatase)

Also Known As:

nucleoside diphosphatase; GDP phosphohydrolase; nucleosidediphosphatase; thiamine diphosphatase

Networked: 16 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Acid Anhydride Hydrolases
      - nucleoside-diphosphatase: 16

Experts

1.	Li, Ying: 1 article (06/2017)
2.	Liu, Anran: 1 article (06/2017)
3.	Liu, Songqin: 1 article (06/2017)
4.	Liu, Yuanjian: 1 article (06/2017)
5.	Ma, Mengyao: 1 article (06/2017)
6.	Mi, Li: 1 article (06/2017)
7.	Wei, Wei: 1 article (06/2017)
8.	Yin, Kaifei: 1 article (06/2017)
9.	Zhang, Yuanjian: 1 article (06/2017)
10.	Fei, Guoqiang: 1 article (01/2017)

Related Diseases

1.	Neoplasms (Cancer) 01/01/1985 - "Sialyltransferase and nucleoside diphosphatase as markers for tumor monitoring." 01/01/1985 - "In this study we report serum sialyltransferase and nucleoside diphosphatase activities of patients with malignant tumors of various primary sites and extent, prior to and during chemotherapy. " 06/22/2017 - "Nucleoside diphosphatase kinase A (NDPK-A) is a metastasis-suppressor protein and a biomarker that act on a wide range cancer cells to inhibit the potential metastasis. "
2.	Alzheimer Disease (Alzheimer's Disease) 01/01/2017 - "Enhanced Activities of Blood Thiamine Diphosphatase and Monophosphatase in Alzheimer's Disease." 12/24/1993 - "Decreased activities of thiamine diphosphatase in frontal and temporal cortex in Alzheimer's disease." 12/24/1993 - "Thiamine diphosphatase (TDPase) activity was measured using a colorimetric assay in frontal and temporal cortex obtained at autopsy from eight patients with neuropathologically confirmed Alzheimer's disease (AD) and from an equal number of control patients matched for age and autopsy delay interval, free from neurological or psychiatric disorders. " 01/01/1985 - "Electron cytochemistry was employed to identify microglial cells by nucleoside diphosphatase (NDPase) in the senile plaques of the autopsy brain in Alzheimer's disease and senile dementia. "
3.	Ganglion Cysts (Ganglion) 01/01/1975 - "Except for nucleoside diphosphatase whose activity in the miracidium was not observed, all the enzymes were most active in the archenteron, protonephridia and nerve ganglion. " 12/22/1990 - "The response of retinal microglial cells, which accompanies retrograde degeneration of ganglion cell axons and perikarya (induced by transection of the optic nerve), was studied in whole-mounted rabbit retinae labeled enzyme-histochemically for nucleoside diphosphatase (NDPase), which is a microglial cell marker. "
4.	Thiamine Deficiency 06/15/1962 - "Thiamine diphosphatase in thiamine deficiency." 05/01/1996 - "Since this action could be related to a brain thiamine deficiency, we measured directly levels of free (nonphosphorylated) thiamine and its phosphate esters, thiamine monophosphate and thiamine diphosphate (TDP), and activities of three TDP-metabolizing enzymes (thiamine pyrophosphokinase, thiamine diphosphatase, and thiamine triphosphatase) in autopsied cerebral cortex of 18 patients with AD and 20 matched controls. "
5.	Neoplasm Metastasis (Metastasis) 06/22/2017 - "Nucleoside diphosphatase kinase A (NDPK-A) is a metastasis-suppressor protein and a biomarker that act on a wide range cancer cells to inhibit the potential metastasis. " 12/01/2010 - "Genes involved in nucleotide metabolism were enriched for the three fluoropyrimidine drugs, with the expression profile for 5FU correlated to an RNA-mediated cytotoxic mechanism, whereas expression of glycosyltransferases (XYLT2) that use UDP sugars as substrates and the nucleoside diphosphatase and metastasis suppressor NM23 (NME1) were associated with FdUMP[10] sensitivity. "

Related Drugs and Biologics

1.	Sialyltransferases
2.	Enzymes
3.	Alkaline Phosphatase
4.	Tumor Suppressor Proteins (Proteins, Tumor Suppressor)
5.	Glycosyltransferases
6.	Macrophage-1 Antigen (Macrophage 1 Antigen)
7.	5'-Nucleotidase (5' Nucleotidase)
8.	Biomarkers (Surrogate Marker)
9.	Uridine Diphosphate Sugars
10.	Thiamin-Triphosphatase (Thiamine Triphosphatase)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Axotomy