4-nitrophenoxycarbonyl methyl disulfide

effective quantitating agent for methanthiolation of sulfhydryl groups; structure given in first source

Also Known As:

NPCMD; para-nitrophenoxycarbonyl methyl disulfide; Carbono(dithioperoxoic) acid, SS-methyl O-(4-nitrophenyl) ester

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Rupture 03/01/2014 - "Inhibition of IL-1β secretion by an endocytosis inhibitor, cytochalasin B, and a lysosomal enzyme cathepsin B inhibitor, CA-074 Me, suggested the involvement of lysosomal rupture and leakage of cathepsin B into the cytosol in NLRP3 activation by NPCMD. "
2.	Neoplasms (Cancer) 03/01/2014 - "The immunopotentiating effect of NPCMD mediated by TLR4 and NLRP3 inflammasome activation could be useful for eliciting effective adaptive immune responses against melanoma and other tumors."
3.	Melanoma (Melanoma, Malignant) 03/01/2014 - "The immunopotentiating effect of NPCMD mediated by TLR4 and NLRP3 inflammasome activation could be useful for eliciting effective adaptive immune responses against melanoma and other tumors." 03/01/2014 - "N-propionyl cysteaminylphenol-maleimide-dextran (NPCMD) is a toxic tyrosinase substrate developed to treat melanoma. "

1.	Inflammasomes
2.	Monophenol Monooxygenase (Tyrosinase)
3.	Enzymes
4.	Dextrans (Dextran)
5.	Cytochalasin B
6.	Cathepsin B
7.	N- (3- propylcarbamoyloxirane- 2- carbonyl)- isoleucyl- proline
8.	maleimide