anordiol (AF 45)

RN given refers to (2alpha,5alpha,17alpha)-isomer

Also Known As:

AF 45; AF-45; H241; 2,17,diethynyl-2,17-dihydroxy-A-norandrostane; A-norandrostane-2 alpha,17 alpha-diethynyl-2 beta,17 beta-diol; H 241; anordiol, (2beta,17alpha)-isomer; anordiol, (2beta,5alpha,17alpha)-isomer; anordiol, (5alpha,17alpha)-isomer; (2 alpha,5 alpha,17 alpha)-2-ethynyl-A-norpregn-20-yne-2,17-diol

Networked: 11 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Norsteroids: 16
      - Norandrostanes
        anordiol: 11

Experts

1.	Bell, Malcolm R: 1 article (01/2020)
2.	Cheungpasitporn, Wisit: 1 article (01/2020)
3.	Deshmukh, Abhishek J: 1 article (01/2020)
4.	Gersh, Bernard J: 1 article (01/2020)
5.	Kumar, Vinayak: 1 article (01/2020)
6.	Mulpuru, Siva K: 1 article (01/2020)
7.	Noseworthy, Peter A: 1 article (01/2020)
8.	Patlolla, Sri Harsha: 1 article (01/2020)
9.	Subramaniam, Anna V: 1 article (01/2020)
10.	Sundaragiri, Pranathi R: 1 article (01/2020)

Related Diseases

1.	Dengue (Dengue Fever) 11/01/1993 - "Mouse-adapted dengue type 4 virus (DEN4) strain H241 is highly neurovirulent for mice, whereas its non-mouse-adapted parent is rarely neurovirulent. " 01/01/1993 - "Differences at 21, 16, and 11 nucleotide positions were noted between dengue 1 Hawaii and S 275/90; dengue 4 H 241 and 814669; Japanese encephalitis Nakayama and JaOArS 982 viral strains, culminating in only 4, 1 and 1 amino acid residue differences, respectively. " 07/01/1984 - "A dengue 4 (strain H241, PDK35-TD3 FRhL p3) vaccine attenuated by passage in primary dog kidney cells followed by passage and final vaccine preparation in DBS-FRhL-2 cells was tested in five yellow fever-immune volunteers. "
2.	Atrial Fibrillation 04/01/2009 - "In our series of 160 patients with paroxysmal atrial fibrillation (AF), 45 ATs were induced by high-current burst pacing after CPVI in 26 patients. " 09/01/2019 - "Three-dimensional left atrium (LA) voltage maps created before an extensive encircling PVI in 64 patients with atrial fibrillation (AF) (45 men, 62 ± 10 years) were examined for an association between electrogram voltage amplitude recorded from the PV-LA junction and acute post-PVI PVRs (spontaneous PVRs and/or ATP-provoked dormant PV conduction). " 11/01/1998 - "To investigate the relationship between left atrial (LA) flow dynamics and hemostatic markers in nonvalvular atrial fibrillation (AF), 45 patients with nonvalvular AF who had not received anticoagulants were evaluated by transesophageal echocardiography. "
3.	Body Weight (Weight, Body) 01/01/1997 - "Significant decrease in the weights of the tests and accessory reproductive organs occurred following anordiol treatment, while the body weights remained at pretreatment level. " 03/01/1994 - "The apparent volume of distribution at steady state (Vss) for anordrin was 276 mL/kg, 7.5% of body weight of the animals; anordrol had a much larger Vss of 4460 mL/kg. The MRT of anordiol after i.m. "
4.	Ventricular Tachycardia 01/01/2020 - "AF (45%), ventricular tachycardia (35%) and ventricular fibrillation (30%) were the most common arrhythmias. "
5.	Yellow Fever 07/01/1984 - "A dengue 4 (strain H241, PDK35-TD3 FRhL p3) vaccine attenuated by passage in primary dog kidney cells followed by passage and final vaccine preparation in DBS-FRhL-2 cells was tested in five yellow fever-immune volunteers. "

Related Drugs and Biologics

1.	Attenuated Vaccines
2.	Vaccines
3.	Testosterone (Sustanon)
4.	Nucleotides
5.	Hemostatics (Antihemorrhagics)
6.	Gonadotropins
7.	Anticoagulants
8.	Amino Acids
9.	Adenosine Triphosphate (ATP)
10.	anordrin (AF 53)

Related Therapies and Procedures

1.	Catheter Ablation
2.	Electric Countershock (Cardioversion)