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fluproquazone (4- (p- fluorophenyl)- 1- isopropyl- 7- methyl- quinazolin- 2(1H)- one)
structure given in first source
Also Known As:
4-(p-fluorophenyl)-1-isopropyl-7-methyl-quinazolin-2(1H)-one
; RF 46-790; 4-(4-fluorophenyl)-7-methyl-1-(1-methylethyl)-2(1H)-quinazolinone
Networked:
13
relevant articles (
5
outcomes,
5
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Heterocyclic Compounds: 198
Fused-Ring Heterocyclic Compounds
2-Ring Heterocyclic Compounds
Quinazolines: 402
Quinazolinones: 124
fluproquazone: 13
Related Diseases
1.
Pain (Aches)
01/01/1981 - "
A double-blind randomized trial was carried out in 59 patient suffering from moderately severe to severe strains and sprains to compare the efficacy of 4-(p-fluorophenyl)-1-isopropyl-7-methyl-2(1H)-quinazolinone (fluproquazone) in the relief of pain.
"
11/01/1986 - "
The study indicates equianalgesia of 100 mg fluproquazone and 500 mg paracetamol which is supported by studies with other pain models.
"
01/01/1981 - "
41 patients suffering from moderate to severe pain were included in a multicentric double-blind study comparing 100 mg 4-(p-fluorophenyl)-1-isopropyl-7-methyl-2(1H)-quinazolinone (fluproquazone) to 250 mg mefenamic acid during a three-day period.
"
06/01/1983 - "
The 100-mg dose of fluproquazone was more effective in relieving episiotomy pain than the 200-mg dose of fluproquazone, aspirin or placebo in terms of mean pain intensity scores after 1 h.
"
06/01/1983 - "
Episiotomy pain: efficacy and safety of fluproquazone compared to aspirin and placebo.
"
2.
Sprains and Strains (Sprain)
01/01/1981 - "
Fluproquazone in the management of strains and sprains.
"
01/01/1981 - "
A double-blind randomized trial was carried out in 59 patient suffering from moderately severe to severe strains and sprains to compare the efficacy of 4-(p-fluorophenyl)-1-isopropyl-7-methyl-2(1H)-quinazolinone (fluproquazone) in the relief of pain.
"
3.
Postoperative Pain
01/01/1981 - "
Comparative study of fluproquazone in the management of post-operative pain.
"
01/01/1981 - "
Clinical evaluation of fluproquazone in post-operative pain.
"
11/01/1986 - "
RF 46-790 versus paracetamol: effect on post-operative pain.
"
01/01/1981 - "
These results indicate a significantly better therapeutic profile for fluproquazone as compared to mefenamic acid in the management of post-operative pain.
"
01/01/1981 - "
Comparison of the analgesic efficacy of fluproquazone, pentazocine and placebo against postoperative pain in neurosurgical patients.
"
4.
Dysmenorrhea (Menstrual Pain)
09/26/1981 - "
[Therapy of dysmenorrhea with prostaglandin synthetase inhibitors: experiences with fluproquazone].
"
09/26/1981 - "
The prostaglandin-synthetase inhibitors fluproquazone and mefenamic acid were evaluated for relief of severe primary and secondary IUD-induced dysmenorrhea in a controlled double-blind cross-over study in 48 patients.
"
09/26/1981 - "
It is concluded that fluproquazone and mefenamic acid are safe and effective in most patients for the relief of primary dysmenorrhea, and that prostaglandin-synthetase inhibitors are a suitable short-term therapy for this syndrome.
"
5.
Headache (Headaches)
01/01/1981 - "
The analgesic activity of 4-(p-fluorophenyl)-1-isopropyl-7-methyl-2(1H)-quinazolinone (fluproquazone) was investigated in three separate controlled studies including 131 outpatients with non-migrainous headache.
"
01/01/1981 - "
Fluproquazone: analgesic activity in outpatients with non-migrainous headache.
"
Related Drugs and Biologics
1.
Analgesics (Analgesic Drugs)
2.
Aspirin (Acetylsalicylic Acid)
3.
Acetaminophen (Paracetamol)
4.
Mefenamic Acid (Pontal)
5.
Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)
6.
Dextropropoxyphene (Darvon)
7.
Pentazocine (Talwin)
8.
Antipyretics
9.
allobarbital (diallyl barbituric acid)
10.
propyphenazone
Related Therapies and Procedures
1.
Episiotomy
2.
Therapeutics
3.
Hysterectomy